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., Wang, P., Song, W., Sun, X. Degradation of regulator of calcineurin 1 (RCAN1) is mediated by both chaperone-mediated autophagy and ubiquitin proteasome pathways. Alzheimer Down syndrome DSCR1 down ...
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RCAN1 (for Regulator of Calcineurin 1) has been endorsed by the HUGO Gene Nomenclature Committee, but ï¬nal approval must await agreement from a majority of researchers in the ï¬eld. The DSCR1 (Adapt78 ...
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1 (RCAN1) expression (Belmont et al., 2008 ). RCAN1 sequesters calcineurin (Belmont et al., 2008 ), a calcium activated protein–phosphatase B, that dephosphorylates Bcl2‐antagonist of cell death (BAD ...
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). A number of genes in this region, including Down syndrome candidate region gene 1 ( DSCR1 , also called Adapt78, RCAN1, MCIP1, or calcipressin 1), may be involved in the production of the DS phenotype. ...
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