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for: cellular and mitochondrial glutathione redox imbalance in
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Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism
James, S. Jill; Rose, Shannon; Melnyk, Stepan; Jernigan, Stefanie; Blossom, Sarah; Pavliv, Oleksandra; Gaylor, David W.
Follow The FASEB Journal , Volume 23 (8): 2374
Fed of American Socs for Experimental Biology – Aug 1, 2009under prooxidant conditions.—James, S. J., Rose, S., Melnyk, S., Jernigan, S., Blossom, S., Pavliv, O., Gaylor, D. W. Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived ...
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Redox imbalance
Daniela, Berg; Moussa, Youdim; Peter, Riederer
Follow Cell and Tissue Research , Volume 318 (1)
Springer Journals – Oct 1, 2004Substantial evidence implies that redox imbalance attributable to an overproduction of reactive oxygen species or reactive nitrogen species that overwhelm the protective defense mechanism of cells ...
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Intracellular redox imbalance and extracellular amino acid metabolic abnormality contribute to arsenic‐induced developmental retardation in mouse preimplantation embryos
Zhang, Chuanling; Liu, Chunmei; Li, Dan; Yao, Nan; Yuan, Xiaohua; Yu, Aiping; Lu, Cailing; Ma, Xu
Follow Journal of Cellular Physiology , Volume 222 (2)
Wiley – Nov 26, 2009that high‐level arsenite induces severe redox imbalance by decreasing the levels of glutathione and increasing the levels of ROS through the oxidative stress adaptor p66Shc, which induces apoptosis ...
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Redox-regulating role of insulin: The essence of insulin effect
Wang, Xin; Tao, Ling; Hai, Chun X.
Follow Molecular and Cellular Endocrinology , Volume 349 (2)
Elsevier – Feb 26, 2012of the regulation on redox balance.2 Oxidative stress and nitrosative stress Oxidative stress is defined as an imbalance between the production of reactive oxygen species (ROS), also known as free ...
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Redox metabolism and malignancy
Grek, Christina L; Tew, Kenneth D
Follow Current Opinion in Pharmacology , Volume 10 (4)
Elsevier – Aug 1, 2010Redox balance underlies cellular homeostasis. Cancer initiation and progression has been linked to the disruption of redox balance and oxidative stress. Recent findings exemplify the distinctive ...
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Redox atlas of the mouse
Godoy, José Rodrigo; Funke, Maria; Ackermann, Waltraud; Haunhorst, Petra; Oesteritz, Sabrina; Capani, Francisco; Elsässer, Hans-Peter; Lillig, Christopher Horst
Follow Biochimica et Biophysica Acta (BBA) - General Subjects , Volume 1810 (1)
Elsevier – Jan 1, 2011Background Oxidoreductases of the thioredoxin family of proteins have been thoroughly studied in numerous cellular and animal models mimicking human diseases. Despite of their well documented role ...
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Pro-oxidant shift in glutathione redox state during aging
Rebrin, Igor; Sohal, Rajindar S.
Follow Advanced Drug Delivery Reviews , Volume 60 (13)
Elsevier – Oct 1, 2008difference between glutathione redox couple and the others, all of which involve one electron transfer reactions.3 Glutathione homeostasisThe intra-cellular concentration of GSH (γ- l ...
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Redox dysregulation, neurodevelopment, and schizophrenia
Do, Kim Q; Cabungcal, Jan H; Frank, Anita; Steullet, Pascal; Cuenod, Michel
Follow Current Opinion in Neurobiology , Volume 19 (2)
Elsevier – Apr 1, 2009In schizophrenia, a developmental redox dysregulation constitutes one ‘hub’ on which converge genetic impairments of glutathione synthesis and environmental vulnerability factors generating oxidative ...
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Redox-sensitive prosurvival and proapoptotic protein expression in the myocardial remodeling post-infarction in rats
Paulo, Schenkel; Angela, Tavares; Rafael, Fernandes; Gabriela, Diniz; Mariane, Bertagnolli; Alex, da Rosa Araujo; Maria, Barreto-Chaves; Maria, Ribeiro; Nadine, Clausell; Adriane, Belló-Klein
Follow Molecular and Cellular Biochemistry , Volume 341 (1)
Springer Journals – Aug 1, 2010. Moreover, we showed a reduction in the GSK-3β phosphorylation and an increase in AIF protein expression in MI group. Taken together, our results show increased H 2 O 2 levels and cellular redox imbalance ...
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Redox‐regulatory mechanisms induced by oxidative stress in Brassica juncea roots monitored by 2‐DE proteomics
Alvarez, Sophie; Galant, Ashley; Jez, Joseph M.; Hicks, Leslie M.
Follow PROTEOMICS , Volume 11 (7)
Wiley – Feb 14, 2011). TRXhs reduce disulfide bonds in a range of proteins to provide a mechanism for regulating redox imbalance 8 . In poplar, mitochondrial TRXh2 contains a glutathionylation site that modifies the redox ...
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