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CD4+ lymphocytes control gut epithelial apoptosis and mediate survival in sepsis
Stromberg, Paul E.; Woolsey, Cheryl A.; Clark, Andrew T.; Clark, Jessica A.; Turnbull, Isaiah R.; McConnell, Kevin W.; Chang, Katherine C.; Chung, Chun-Shiang; Ayala, Alfred; Buchman, Timothy G.; Hotchkiss, Richard S.; Coopersmith, Craig M.
Follow The FASEB Journal , Volume 23 (6): 1817
Fed of American Socs for Experimental Biology – Jun 1, 2009., Hotchkiss, R. S., Coopersmith, C. M. CD4 + lymphocytes control gut epithelial apoptosis and mediate survival in sepsis. crosstalk intestine Bcl-2 cell death cecal ligation and puncture crosstalk regularly ...
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Intestinal epithelial barrier and mucosal immunity
B., Dubois; A., Goubier; G., Joubert; D., Kaiserlian
Follow Cellular and Molecular Life Sciences , Volume 62 (12)
Springer Journals – Jun 1, 2005cells [39]. Clonal deletion by apoptosis has been demonstrated in CD4+ T lymphocytes of T cell receptor (TCR) transgenic mice using various model Ags, including ovalbumin (OVA) [40], myelin basic protein ...
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Clinical applications and availability of CD4+ T cell count testing in sub‐Saharan Africa
Taiwo, Babafemi O.; Murphy, Robert L.
Follow Cytometry Part B , Volume 74B (S1)
Wiley – Mar 19, 2008The absolute CD4+ T cell count in adults and CD4+ T cell percentage of lymphocytes (CD4%) in pediatrics compliment clinical history and physical examination to inform decisions about initiating ...
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Autoimmunity, autoinflammation and lymphoma in combined immunodeficiency (CID)
Schuetz, Catharina; Niehues, Tim; Friedrich, Wilhelm; Schwarz, Klaus
Follow Autoimmunity Reviews , Volume 9 (7)
Elsevier – May 1, 2010lymphocyte apoptosis (“clonal deletion”) or via receptor editing through secondary V(D)J recombination of TCR or BCR genes creating a new receptor with altered binding capability. Two further mechanisms ...
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Pathological versus protective functions of IL-22 in airway inflammation are regulated by IL-17A
Sonnenberg, Gregory F.; Nair, Meera G.; Kirn, Thomas J.; Zaph, Colby; Fouser, Lynette A.; Artis, David
Follow The Journal of Experimental Medicine , Volume 207 (6): 1293
Rockefeller University Press – Jun 7, 2010in the absence of IL-17A. Finally, in an in vitro culture system, IL-22 administration protected airway epithelial cells from bleomycin-induced apoptosis, and this protection was reversed after coadministration ...
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First French-Argentine Immunology Congress, 2010 Abstracts Held on Buenos Aires, Argentina, 2nd-5th november, 2010
Shahzad, Aamir
Follow Translational Biomedicine , Volume 1 (2)
iMedPub, Internet Medical Publishing – Sep 8, 2010on cell mediated immunity. Thus, activated specific T lymphocytes display a crucial role in the immune response of the host against the pathogen. In particular, CD4+ IFNγ secreting T cells display a main ...
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Leukocyte apoptosis and its significance in sepsis and shock
Wesche, Doreen E.; Lomas-Neira, Joanne L.; Perl, Mario; Chung, Chun-Shiang; Ayala, Alfred
Follow Journal of Leukocyte Biology , Volume 78 (2): 325
Fed of American Socs for Experimental Biology – Aug 1, 2005-associated anemia. Studies of septic animals given iron after CLP indicate that iron treatment decreases survival, facilitates bacterial growth, and increases gut epithelial and splenic lymphocyte apoptosis ...
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Deficiency of γδ T lymphocytes contributes to mortality and immunosuppression in sepsis
Chung, Chun-Shiang; Watkins, Lara; Funches, Antonio; Lomas-Neira, Joanne; Cioffi, William G.; Ayala, Alfred
Follow AJP - Regulatory, Integrative and Comparative Physiology , Volume 291 (5): R1338
The American Physiological Society – Nov 1, 2006lymphocytes (IEL), which are rich in γδ T cells, within the small intestine illustrated a significant increase in apoptosis and immune dysfunction in mice subjected to sepsis. However, the contribution of γδ T ...
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Renal allograft rejection: The contribution of chemokines to the adhesion and retention of αE(CD103)β7 integrin-expressing intratubular T cells
Al-Hamidi, Abdulaziz; Pekalski, Marcin; Robertson, Helen; Ali, Simi; Kirby, John A.
Follow Molecular Immunology , Volume 45 (15)
Elsevier – Sep 1, 2008of chemokines such as CCL7, which are also expressed within tubules during renal allograft rejection. 1 IntroductionNormal renal tubules are not infiltrated by T lymphocytes but both CD4+ and CD8+ T ...
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Follow Surgery , Volume 146 (6)
Elsevier – Dec 1, 2009combined chemotherapy protocols An antiendothelial combination therapy strategy to increase survival in experimental pancreatic cancer (Schwarz et al). 2009;146:241-9 Apoptosis ERBB2 suppression decreases ...
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