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the opposite effect of RA. Furthermore, RA ameliorated TNBS-induced colitis in a dose-dependent manner, as seen by improved body weight and colon inflammation. RA down-regulates colon inflammatory responses ...
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, possibly by generating reactive oxygen species. All- trans retinoic acid (ATRA) was assessed as a prospective therapeutic agent for reversing reproductive disorders. Introduction Chronic arsenic ...
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Chemopreventive approaches for the treatment of breast cancer have been validated clinically and with in vitro studies. The combined action of tamoxifen/all‐trans retinoic acid was advantageous ...
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(T1D), in this study we examined the potential role for retinoids, etretinate and all- trans -retinoic acid (ATRA) in preclinical models of human T1D. When administered prophylactically to CBA/H mice ...
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or the macrophage stage (following differentiation with all-trans retinoic acid). Effects on cell surface markers involved in macrophage activation and adhesion were also examined. Both soy and dairy ferments ...
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of docosahexaenoic acid metabolism are named as docosanoids. They include resovins, protectins (neuroprotectins), and maresins. Docosanoids produce antioxidant, anti-inflammatory, and antiapoptotic effects in brain ...
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of untreated C3H10T1/2 cells. Checkerboard assays indicated that all three isoforms also stimulated chemokinesis of the untreated cells. C3H10T1/2 cells treated with all‐trans‐retinoic acid (ATRA) and expressing ...
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regulated by RA are up-regulated through the binding of retinoid-activated nuclear receptors to direct repeat (DR) retinoic acid response elements (RAREs) [35,36] which typically are located in the 5 ...
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mice LC deficiency Footnotes CD62L CD62 ligand 51 Cr 51 Chromium DT diphtheria toxin DTA diphtheria toxin subunit A DTR diphtheria toxin receptor MFI mean fluorescence intensity Rae-1 retinoic acid early ...
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-inducible antioxidant genes, all of which have been reported previously to be regulated by nuclear factor erythroid-related factor 2 (Nrf2), a transcription factor that is critical to the lung antioxidant ...
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