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for: adenosine a2a receptors play an active role in mouse bone marrow
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Adenosine A2A receptors play an active role in mouse bone marrow-derived mesenchymal stem cell development
Katebi, Majid; Soleimani, Mansooreh; Cronstein, Bruce N.
Follow Journal of Leukocyte Biology , Volume 85 (3): 438
Fed of American Socs for Experimental Biology – Mar 1, 2009and adenosine A 2A R play a critical role in promoting the proliferation and differentiation of mouse BM-MSCs. Abstract Bone marrow-derived mesenchymal stem cells (BM-MSCs) play a role in wound healing ...
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Adenosine A2A receptor activation limits graft-versus-host disease after allogenic hematopoietic stem cell transplantation
Lappas, Courtney M.; Liu, Po-Ching; Linden, Joel; Kang, Elizabeth M.; Malech, Harry L.
Follow Journal of Leukocyte Biology , Volume 87 (2): 345
Fed of American Socs for Experimental Biology – Feb 1, 2010-elevating agents are known to induce alloantigen-specific T cell hyporesponsiveness and prevent GVHD lethality in murine models [ 12 ] . As the activation of the G s -coupled adenosine A 2A R plays a role ...
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On the role of subtype selective adenosine receptor agonists during proliferation and osteogenic differentiation of human primary bone marrow stromal cells
Costa, M. Adelina; Barbosa, A.; Neto, E.; Sá‐e‐Sousa, A.; Freitas, R.; Neves, J.M.; Magalhães‐Cardoso, T.; Ferreirinha, F.; Correia‐de‐Sá, P.
Follow Journal of Cellular Physiology , Volume 226 (5)
Wiley – Feb 22, 2011nature of this process suggests that autocrine/paracrine stimuli play a fundamental role in activating focal areas of bone tissue challenged by circulating factors, namely parathyroid hormone ...
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Adenosine A2A receptor activation attenuates inflammation and injury in diabetic nephropathy
Awad, Alaa S.; Huang, Liping; Ye, Hong; Duong, Elizabeth Thu Anh; Bolton, W. Kline; Linden, Joel; Okusa, Mark D.
Follow AJP - Renal Physiology , Volume 290 (4): F828
The American Physiological Society – Apr 1, 2006) that may play a pivotal role in the development and progression of diabetic nephropathy. These data support the role of macrophages and potentially other bone marrow-derived cells in the genesis ...
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A2A receptors in inflammation and injury: lessons learned from transgenic animals
Haskó, György; Pacher, Pál
Follow Journal of Leukocyte Biology , Volume 83 (3): 447
Fed of American Socs for Experimental Biology – Mar 1, 2008as the primary anti-inflammatory effectors of extracellular adenosine. This broad, anti-inflammatory effect of A 2A receptor activation is a result of the predominant expression of A 2A receptors on monocytes ...
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P2X7 receptor drives osteoclast fusion by increasing the extracellular adenosine concentration
Pellegatti, Patrizia; Falzoni, Simonetta; Donvito, Giovanna; Lemaire, Irma; Di Virgilio, Francesco
Follow The FASEB Journal , Volume 25 (4): 1264
Fed of American Socs for Experimental Biology – Apr 1, 2011of the adenosine A2A receptor increases, while selective A2A blockade inhibits, fusion. These results show that the purinergic axis plays a crucial and as yet undescribed role in osteoclast formation and reconcile ...
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Adenosine A2A receptor activation reduces hepatic ischemia reperfusion injury by inhibiting CD1d-dependent NKT cell activation
Lappas, Courtney M.; Day, Yuan-Ji; Marshall, Melissa A.; Engelhard, Victor H.; Linden, Joel
Follow The Journal of Experimental Medicine , Volume 203 (12): 2639
Rockefeller University Press – Nov 27, 2006or activation of adenosine A 2A receptors (A 2A Rs) with the selective agonist 4- {3-6-amino-9-(5-ethylcarbamoyl-3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-yl- prop-2-ynyl}-cyclohexanecarboxylic acid methyl ...
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Mechanisms of induction of adenosine receptor genes and its functional significance
St. Hilaire, Cynthia; Carroll, Shannon H.; Chen, Hongjie; Ravid, Katya
Follow Journal of Cellular Physiology , Volume 218 (1)
Wiley – Oct 27, 2008ishcemic events by A 2A AR appear to be mediated by activity of this receptor on bone marrow‐derived cells (Day et al., 2005 ; Yang et al., 2005 ), suggesting that the modulation of the receptors on bone ...
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Enhanced mast cell activation in mice deficient in the A2b adenosine receptor
Hua, Xiaoyang; Kovarova, Martina; Chason, Kelly D.; Nguyen, MyTrang; Koller, Beverly H.; Tilley, Stephen L.
Follow The Journal of Experimental Medicine , Volume 204 (1): 117
Rockefeller University Press – Jan 22, 2007of the mast cell to antigen-mediated degranulation through this pathway can be dramatically influenced by the A2b adenosine receptor. Loss of this G s -coupled receptor on mouse bone marrow–derived mast cells ...
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Cholera toxin inhibits IL-12 production and CD8α+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function
la Sala, Andrea; He, Jianping; Laricchia-Robbio, Leopoldo; Gorini, Stefania; Iwasaki, Akiko; Braun, Michael; Yap, George S.; Sher, Alan; Ozato, Keiko; Kelsall, Brian
Follow The Journal of Experimental Medicine , Volume 206 (6): 1227
Rockefeller University Press – Jun 8, 2009-adrenergic agonists, adenosine, cannabinoids, and opiates, as well as by the cell-permeable cAMP analogue dbcAMP, suggests that the direct induction of cAMP by Gs protein activation plays a key role in CT ...
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