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for: activation of ets 2 by oxidative stress induces bcl xl expression and
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Activation of Ets-2 by oxidative stress induces Bcl-xL expression and accounts for glial survival in amyotrophic lateral sclerosis
Lee, Junghee; Kannagi, Mari; Ferrante, Robert J.; Kowall, Neil W.; Ryu, Hoon
Follow The FASEB Journal , Volume 23 (6): 1739
Fed of American Socs for Experimental Biology – Jun 1, 2009., Ryu, H. Activation of Ets-2 by oxidative stress induces Bcl-xL expression and accounts for glial survival in amyotrophic lateral sclerosis. Abstract Amyotrophic lateral sclerosis (ALS ...
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Silymarin modulates doxorubicin-induced oxidative stress, Bcl-xL and p53 expression while preventing apoptotic and necrotic cell death in the liver
Patel, Nirav; Joseph, Cecil; Corcoran, George B.; Ray, Sidhartha D.
Follow Toxicology and Applied Pharmacology , Volume 245 (2)
Elsevier – Jun 1, 2010whether pre-exposures to SMN can prevent hepatotoxicity by reducing Dox-induced free radical mediated oxidative stress, by modulating expression of apoptotic signaling proteins like Bcl-xL ...
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Bcl-xL transformed peanut ( Arachis hypogaea L.) exhibits paraquat tolerance
Y., Chu; X., Deng; P., Faustinelli; P., Ozias-Akins
Follow Plant Cell Reports , Volume 27 (1)
Springer Journals – Jan 1, 2008in these lines. A high level of Bcl-xL transgene expression may be deleterious to plant growth and development even though the gene may confer tolerance to other abiotic and biotic stresses such as drought ...
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Oxidative stress and diabetes mellitus
Yang, Hui; Jin, Xun; Kei Lam, Christopher Wai; Yan, Sheng-Kai
Follow Clinical Chemistry and Laboratory Medicine , Volume 49 (11)
de Gruyter – Nov 1, 2011by these conditions whereas B-cell lymphoma-extra large (Bcl-xL) was reduced. Loss of b cell Figure 2 Hyperglycemia-induced ROS generation and consequent activation of pathological pathways. Modified from references ...
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Pre-exposure to a novel nutritional mixture containing a series of phytochemicals prevents acetaminophen-induced programmed and unprogrammed cell deaths by enhancing BCL-XL expression and minimizing
Sidhartha, Ray; Nirav, Patel; Nilank, Shah; Akila, Nagori; Anne, Naqvi; Sidney, Stohs
Follow Molecular and Cellular Biochemistry , Volume 293 (1)
Springer Journals – Dec 1, 2006oxidative stress and genomic DNA fragmentation preceding liver injury. Liver homogenates subjected to western blot analysis disclosed the ability of 1X-PNM to counteract APAP-induced decrease in Bcl-xL ...
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Catalpol inhibits apoptosis in hydrogen peroxide-induced endothelium by activating the PI3K/Akt signaling pathway and modulating expression of Bcl-2 and Bax
Hu, Lingai; Sun, Yukun; Hu, Jian
Follow European Journal of Pharmacology , Volume 628 (1)
Elsevier – Feb 25, 2010the expression of Bcl-2, while decreasing Bax expression, but also induced Akt activation and Bad phosphorylation, and ultimately reduced H 2 O 2 -induced apoptosis. The protective effects of catalpol were ...
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Doxycycline suppresses doxorubicin-induced oxidative stress and cellular apoptosis in mouse hearts
Lai, Hui-Chin; Yeh, Yueh-Chiao; Ting, Chih-Tai; Lee, Wen-Lieng; Lee, Hsiao-Wei; Wang, Li-Chuan; Wang, Kuo-Yang; Lai, Hui-Chun; Wu, Angie; Liu, Tsun-Jui
Follow European Journal of Pharmacology , Volume 644 (1)
Elsevier – Oct 10, 2010pathways were also activated in the hearts of doxorubicin-treated mice as reflected by decreased Bcl-2/Bcl- XL and elevated Bax/Bad, p53/Apaf-1, endoplasmic reticulum glucose-related protein 78, C/EBP ...
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Bcl-2 overexpression in type II epithelial cells does not prevent hyperoxia-induced acute lung injury in mice
Métrailler-Ruchonnet, Isabelle; Pagano, Alessandra; Carnesecchi, Stéphanie; Khatib, Karim; Herrera, Pedro; Donati, Yves; Bron, Camille; Barazzone, Constance
Follow AJP - Lung Cellular and Molecular Physiology , Volume 299 (3): L312
The American Physiological Society – Sep 1, 2010Abstract Bcl-2 is an anti-apoptotic molecule preventing oxidative stress damage and cell death. We have previously shown that Bcl-2 is able to prevent hyperoxia-induced cell death when overexpressed ...
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Taurine exerts hypoglycemic effect in alloxan-induced diabetic rats, improves insulin-mediated glucose transport signaling pathway in heart and ameliorates cardiac oxidative stress and apoptosis
Das, Joydeep; Vasan, Vandana; Sil, Parames C.
Follow Toxicology and Applied Pharmacology , Volume 258 (2)
Elsevier – Jan 15, 2012insulin content, enhanced the levels of cardiac damage markers and altered lipid profile in the plasma. Moreover, it increased oxidative stress (decreased antioxidant enzyme activities and GSH/GSSG ratio ...
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Rasagiline protects against alpha-synuclein induced sensitivity to oxidative stress in dopaminergic cells
Chau, K.Y.; Cooper, J.M.; Schapira, A.H.V.
Follow Neurochemistry International , Volume 57 (5)
Elsevier – Nov 1, 2010be mediated by activation of Bcl-2 and Bcl-xL and the protein kinase C/mitogen-activated protein kinase (PKC/MAPK) pathway, and down-regulation of pro-apoptotic molecules such as Bax and Bad ( Mandel et al ...
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