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    Kulstad, J. Jacob

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1 - 8 of 8 results found

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    More Like This bw1RGEiDa7 FREE

    Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer mice.

    Pedersen, Ward A.; McMillan, Pamela J.; Kulstad, J. Jacob; Leverenz, James B.; Craft, Suzanne; Haynatzki, Gleb R.
    Experimental neurology
    MEDLINE Abstracts – Jun 1, 2006

    The thiazolidinediones, such as rosiglitazone, increase peripheral insulin sensitivity and their use is proposed for the treatment of Alzheimer's disease ...

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    More Like This fxEnMbMduh FREE

    Combined statin and niacin therapy remodels the high-density lipoprotein proteome.

    Green, Pattie S.; Vaisar, Tomas; Pennathur, Subramaniam; Kulstad, J. Jacob; Moore, Andrew B.; Marcovina, Santica; Brunzell, John; Knopp, Robert H.; Zhao, Xue-Qiao; Heinecke, Jay W.
    Circulation
    MEDLINE Abstracts – Sep 16, 2008

    BACKGROUND: Boosting low high-density lipoprotein (HDL) levels is a current strategy for preventing clinical events that result from cardiovascular disease ...

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    More Like This JhXhHm4BLs FREE

    Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 allele.

    Cook, David G.; Leverenz, James B.; McMillan, Pamela J.; Kulstad, J. Jacob; Ericksen, Sasha; Roth, Richard A.; Schellenberg, Gerard D.; Jin, Lee-Way; Kovacina, Kristina S.; Craft, Suzanne
    The American journal of pathology
    MEDLINE Abstracts – Jan 1, 2003

    Abeta is the major component of amyloid plaques characterizing Alzheimer's disease (AD). Abeta accumulation can be affected by numerous factors ...

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    More Like This J0r57S12lw FREE

    Effects of chronic glucocorticoid administration on insulin-degrading enzyme and amyloid-beta peptide in the aged macaque.

    Kulstad, J. Jacob; McMillan, Pamela J.; Leverenz, James B.; Cook, David G.; Green, Pattie S.; Peskind, Elaine R.; Wilkinson, Charles W.; Farris, Wesley; Mehta, Pankaj D.; Craft, Suzanne
    Journal of neuropathology and experimental neurology
    MEDLINE Abstracts – Feb 1, 2005

    Insulin-degrading enzyme (IDE) has been identified as a candidate protease in the clearance of amyloid-delta (Abeta) peptides from the ...

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    More Like This sxSEpZBl2L Preview Only

    Reduced Hippocampal Insulin-Degrading Enzyme in Late-Onset Alzheimer's Disease Is Associated with the Apolipoprotein E-{epsilon}4 Allele

    Cook, David G.; Leverenz, James B.; McMillan, Pamela J.; Kulstad, J. Jacob; Ericksen, Sasha; Roth, Richard A.; Schellenberg, Gerard D.; Jin, Lee-Way; Kovacina, Kristina S.; Craft, Suzanne
    American Journal of Pathology , Volume 162 (1): 313
    American Society for Investigative Pathology – Jan 1, 2003

    David G. Cook * , James B. Leverenz ¶|| , Pamela J. McMillan *¶ , J. Jacob Kulstad *** , Sasha Ericksen ¶ , Richard A. Roth , Gerard ...

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    More Like This 0iGoL7qGuw FREE

    Peripheral amyloid-beta levels regulate amyloid-beta clearance from the central nervous system.

    Marques, Marcos A.; Kulstad, J. Jacob; Savard, Christopher E.; Green, Pattie S.; Lee, Sum P.; Craft, Suzanne; Watson, G. Stennis; Cook, David G.
    Journal of Alzheimer's disease : JAD
    MEDLINE Abstracts – Feb 1, 2009

    Amyloid-beta (Abeta) is cleared from the brain by both proteolytic digestion and transport across the blood-brain-barrier into the ...

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    More Like This F452gCGksx FREE

    Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: a preliminary study.

    Watson, G. Stennis; Cholerton, Brenna A.; Reger, Mark A.; Baker, Laura D.; Plymate, Stephen R.; Asthana, Sanjay; Fishel, Mark A.; Kulstad, J. Jacob; Green, Pattie S.; Cook, David G.; Kahn, Steven E.; Keeling, Michelle L.; Craft, Suzanne
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
    MEDLINE Abstracts – Nov 1, 2005

    OBJECTIVE: Insulin resistance (impaired insulin action) has been associated with Alzheimer disease (AD) and memory impairment, independent of AD. Peroxisome proliferator ...

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    More Like This 3OsXb2Q02x FREE

    Hyperinsulinemia provokes synchronous increases in central inflammation and beta-amyloid in normal adults.

    Fishel, Mark A.; Watson, G. Stennis; Montine, Thomas J.; Wang, Qin; Green, Pattie S.; Kulstad, J. Jacob; Cook, David G.; Peskind, Elaine R.; Baker, Laura D.; Goldgaber, Dmitry; Nie, Wei; Asthana, Sanjay; Plymate, Stephen R.; Schwartz, Michael W.; Craft, Suzanne
    Archives of neurology
    MEDLINE Abstracts – Oct 1, 2005

    BACKGROUND: Inflammation has been implicated as a pathogenetic factor in Alzheimer disease, possibly via effects on beta-amyloid (Abeta). Hyperinsulinemia induces ...

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