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J. Autian (1967)
Toxicologic aspects of implants.Journal of biomedical materials research, 1 4
R. Wilsnack, F. Meyer, J. Smith (1973)
Human cell culture toxicity testing of medical devices and correlation to animal tests.Biomaterials, medical devices, and artificial organs, 1 3
A. S. Chawla (1978)
A Novel Filler Free Silicone Rubber Biomaterial II. Radiation Chemical and Physical Evaluation, 2
R. Johnsson, A. Hegyeli (1968)
TISSUE CULTURE TECHNIQUES FOR SCREENING OF PROSTHETIC MATERIALS *Annals of the New York Academy of Sciences, 146
A. S. Chawla (1978)
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M. Tollar, M. Stol, K. Kliment (1969)
Surgical suture materials coated with a layer of hydrophilic Hydron gel.Journal of biomedical materials research, 3 2
S. A. Rosenbluth, G. R. Weddington, W. L. Guess, J. Autian (1965)
Tissue Culture Method for Screening Toxicity of Plastic Materials to be Used in Medical Practice, 54
S. A. O'Bannon, A. Thompson, R. Hodge, M. E. Estrella (1970)
Rapid In Vitro Screening of Polymers for Biocompatibility, A4
A. S. Chawla (1976)
Pure and Filler Free Silicone Rubber Biomaterial: A New Concept in Preparing Silicone Rubber, 1
R. Johnsson-Hegyeli, A. Hegyeli (1969)
Interaction of blood and tissue cells with foreign surfaces.Journal of biomedical materials research, 3 1
W. L. Guess, S. A. Rosenbluth, B. Schmidt, J. Autian (1965)
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D. Powell, W. Lawrence, J. Turner, J. Autian (1970)
Development of a toxicity evaluation program for dental materials and products. I. Screening for irritant responses.Journal of biomedical materials research, 4 4
Charles Homsy (1970)
Bio-compatibility in selection of materials for implantation.Journal of biomedical materials research, 4 3
A. Chawla (1978)
In vivo interactions between novel filler free silicone rubber and blood.Biomaterials, medical devices, and artificial organs, 6 2
Cytotoxicity of a novel filler free silicone rubber (FFSR) was evaluated by studying its effect on mouse L929 cells. Silastic and a laboratory rubber tubing (RT) were used as control materials. Three different experimental methods were used. In method A, after six days of cell culturing in the sample extracts, there were 95, 80, and 50% of control viable cells for FFSR, Silastic, and RT, respectively. Similarly, in method B, after six days of direct contact between samples and the cells, there were 80, 40, and 20% of control viable cells for FFSR, Silastic, and RT, respectively. For the Agar Overlay Test, method C, the cells under the FFSR samples were normal and healthy compared to those under Silastic and RT. From these studies it was concluded that FFSR had the least cytotoxicity of the three materials studied.
Journal of Biomedical Materials Research Part A – Wiley
Published: Jul 1, 1982
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