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References (39)
-
Ji Lin, H. Arnold, M. Della-Fera, M. Azain, D. Hartzell, C. Baile (2002)
Myostatin knockout in mice increases myogenesis and decreases adipogenesis.Biochemical and biophysical research communications, 291 3
-
R Hanset, C Michaux, C Dessy‐Doize, G Burtonboy (1982)
Muscle hypertrophy of genetic origin and its use to improve beef productionGenome Res
-
A. Utomo, A. Nikitin, Wen-Hwa Lee (1999)
Temporal, spatial, and cell type–specific control of Cre-mediated DNA recombination in transgenic miceNature Biotechnology, 17
-
SB Needleman, CD Wunsch (1970)
A general method applicable to the search for similarities in the amino acid sequence of two proteinsJ Cell Physiol, 48
-
S. Needleman, C. Wunsch (1970)
A general method applicable to the search for similarities in the amino acid sequence of two proteins.Journal of molecular biology, 48 3
-
A. Mcpherron, Se-Jin Lee (1997)
Double muscling in cattle due to mutations in the myostatin gene.Proceedings of the National Academy of Sciences of the United States of America, 94 23
-
M Sharma, R Kambadur, KG Matthews, WG Somers, GP Devlin, JV Conaglen, PJ Fowke, JJ Bass (1999)
Myostatin, a transforming growth factor beta superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarctJ Anim Sci, 180
-
A. Mcpherron, Se-Jin Lee (2002)
Suppression of body fat accumulation in myostatin-deficient mice.The Journal of clinical investigation, 109 5
-
R. Torres, R. Kühn (1997)
Laboratory Protocols for Conditional Gene Targeting -
Se-Jin Lee, A. Mcpherron (2001)
Regulation of myostatin activity and muscle growthProceedings of the National Academy of Sciences of the United States of America, 98
-
J Sambrook, DW Russel (2001)
Molecular cloning, a laboratory manualMamm Genome
-
G Szabo, G Dallmann, G Muller, L Patthy, M Soller, L Varga (1998)
A deletion in the myostatin gene causes the compact (Cmpt) hypermuscular mutation in miceCardiovasc Res, 9
-
T. Zimmers, M. Davies, L. Koniaris, Paul Haynes, A. Esquela, K. Tomkinson, A. Mcpherron, N. Wolfman, Se-Jin Lee (2002)
Induction of Cachexia in Mice by Systemically Administered MyostatinScience, 296
-
M. Ansay, R. Hanset (1979)
Anatomical, physiological and biochemical differences between conventional and double-muscled cattle in the Belgian Blue and White breed.Livestock Production Science, 6
-
Kimi Araki, M. Araki, Jun-ichi Miyazaki, Pierre Vassalli (1995)
Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase.Proceedings of the National Academy of Sciences of the United States of America, 92 1
-
AC McPherron, S‐J Lee (2002)
Suppression of body fat accumulation in myostatin‐deficient miceProc Natl Acad Sci USA, 109
-
Mridula Sharma, R. Kambadur, K. Matthews, W. Somers, G. Devlin, J. Conaglen, P. Fowke, J. Bass (1999)
Myostatin, a transforming growth factor‐β superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarctJournal of Cellular Physiology, 180
-
R. Hanset, C. Michaux, C. Dessy-Doizé, G. Burtonboy (1982)
Studies on the 7th Rib Cut in Double Muscled and Conventional Cattle. Anatomical, Histological and Biochemical Aspects -
Xiaolei Zhu, Michele Hadhazy, M. Wehling, J. Tidball, E. McNally (2000)
Dominant negative myostatin produces hypertrophy without hyperplasia in muscleFEBS Letters, 474
-
Jinzeng Yang, T. Ratovitski, J. Brady, M. Solomon, K. Wells, R. Wall (2001)
Expression of myostatin pro domain results in muscular transgenic miceMolecular Reproduction and Development, 60
-
J. Wegner, E. Albrecht, I. Fiedler, F. Teuscher, H. Papstein, K. Ender (2000)
Growth- and breed-related changes of muscle fiber characteristics in cattle.Journal of animal science, 78 6
-
R Kambadur, M Sharma, TPL Smith, JJ Bass (1997)
Mutations in myostatin (GDF8) in double‐muscled Belgian Blue CattleBiochem Biophys Res Commun, 7
-
H Schmalbruch, U Hellhammer (1977)
The number of nuclei in adult rat muscles with special reference to satellite cellsNat Biotechnol, 189
-
B. Hogan, F. Costantini, E. Lacy (1986)
Manipulating the mouse embryo: A laboratory manual -
A. Mcpherron, A. Lawler, Se-Jin Lee (1997)
Regulation of skeletal muscle mass in mice by a new TGF-p superfamily membernature, 387
-
A. Nagy, J. Rossant, R. Nagy, W. Abramow-Newerly, J. Roder (1993)
Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.Proceedings of the National Academy of Sciences of the United States of America, 90 18
-
L Grobet, D Poncelet, LJ Royo Martin, B Brouwers, D Pirottin, C Michaux, F Menissier, M Zanotti, S Dunner, M Georges (1998)
Molecular definition of an allelic series of mutations disrupting the myostatin function and causing double‐muscling in cattleMamm Genome, 9
-
R. Kambadur, Mridula Sharma, T. Smith, J. Bass (1997)
Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle.Genome research, 7 9
-
L. Grobet, L. Martin, D. Poncelet, Dimitri Pirottin, B. Brouwers, J. Riquet, A. Schoeberlein, S. Dunner, F. Ménissier, J. Masabanda, R. Fries, R. Hanset, M. Georges (1997)
A deletion in the bovine myostatin gene causes the double–muscled phenotype in cattleNature Genetics, 17
-
A Nagy, J Rossant, R Nagy, W Abramow‐Newerly, JC Roder (1993)
Derivation of completely cell culture‐derived mice from early passage embryonic stem cellsAnat Rec, 90
-
H. Schmalbruch, U. Hellhammer (1977)
The number of nuclei in adult rat muscles with special reference to satellite cellsThe Anatomical Record, 189
-
H. Gu, Y. Zou, K. Rajewsky (1993)
Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targetingCell, 73
-
L Grobet, LJ Royo Martin, D Poncelet, D Pirottin, B Brouwers, J Riquet, A Schoeberlein, S Dunner, F Ménissier, J Massabanda, R Fries, R Hanset, M Georges (1997)
A deletion in the myostatin gene causes double‐muscling in cattleNat Genet, 17
-
J Lin, HB Arnold, MA Della‐Fera, MJ Azain, DL Hartzell, CA Baile (2002)
Myostatin knockout in mice increases myogenesis and decreases adipogenesisJ Clin Invest, 291
-
AR Utomo, AY Nikitin, WH Lee (1999)
Temporal, spatial, and cell type‐specific control of Cre‐mediated DNA recombination in transgenic miceFEBS Lett, 17
-
Gyula Szabo, G. Dallmann, G. Müller, L. Patthy, M. Soller, L. Varga (1998)
A deletion in the myostatin gene causes the compact (Cmpt) hypermuscular mutation in miceMammalian Genome, 9
-
Sheng-Qian Wu, R. Hopfner, J. Mcneill, T. Wilson, V. Gopalakrishnan (2000)
Altered paracrine effect of endothelin in blood vessels of the hyperinsulinemic, insulin resistant obese Zucker rat.Cardiovascular research, 45 4
-
S. Bogdanovich, T. Krag, E. Barton, Linda Morris, Lisa-Anne Whittemore, R. Ahima, T. Khurana (2002)
Functional improvement of dystrophic muscle by myostatin blockadeNature, 420
-
J. Brüning, M. Michael, J. Winnay, Tatsuya Hayashi, Dieter Hörsch, D. Accili, L. Goodyear, C. Kahn (1998)
A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance.Molecular cell, 2 5
- Publisher
- Wiley
- Copyright
- Copyright © 2003 Wiley Subscription Services, Inc., A Wiley Company
- ISSN
- 1526-954X
- eISSN
- 1526-968X
- DOI
- 10.1002/gene.10188
- pmid
- 12717734
- Publisher site
- See Article on Publisher Site
Abstract
By using a conditional gene targeting approach exploiting the cre‐lox system, we show that postnatal inactivation of the myostatin gene in striated muscle is sufficient to cause a generalized muscular hypertrophy of the same magnitude as that observed for constitutive myostatin knockout mice. This formally demonstrates that striated muscle is the production site of functional myostatin and that this member of the TGFβ family of growth and differentiation factors regulates muscle mass not only during early embryogenesis but throughout development. It indicates that myostatin antagonist could be used to treat muscle wasting and to promote muscle growth in man and animals. genesis 35:227–238, 2003. © 2003 Wiley‐Liss, Inc.
Journal
Genesis: the Journal of Genetics and Development – Wiley
Published: Apr 1, 2003
Keywords: ; ; ;