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J. B. Murray, L. Brown, R. Langer, M. Klagsburn (1983)
A micro sustained release system for epidermal growth factor, 19
J. R. Robinson (1978)
Sustained and Controlled Release Drug Delivery Systems
R. Langer, E. R. Edelman, D. Hsieh (1983)
Biocompatible Polymers, Metals, and Composites
D. Hsieh, R. Langer, J. Folkman (1981)
Magnetic modulation of release of macromolecules from polymers, 78
W. Rhine, D. Hsieh, R. Langer (1980)
Polymers for sustained macromolecule release: procedures to fabricate reproducible delivery systems and control release kinetics.Journal of pharmaceutical sciences, 69 3
J. Murray, L. Brown, R. Langer (1984)
Controlled release of microquantities of macromolecules.Cancer drug delivery, 1 2
L. Brown, C. Wei, R. Langer (1983)
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A. C. Guyton (1986)
Textbook of Medical Physiology
E. Edelman, E. Edelman, Joseph Kost, Joseph Kost, H. Bobeck, Robert Langer, Robert Langer (1985)
Regulation of drug release from polymer matrices by oscillating magnetic fields.Journal of biomedical materials research, 19 1
The kinetics of drug release from polymerdrug matrices containing an embedded magnet was continuously monitored in vitro and in vivo. The application of an oscillating magnetic field increased the rate of drug release from the polymer matrices. Within the limits of detection the increase in release occurred immediately, remained stable for as long as the field was applied, and returned exactly to baseline upon withdrawal of the field. The increase in release was directly proportional to field amplitude. The same pattern of results were observed in vivo as in vitro, though higher strength fields were required in vivo to achieve the same effect observed in vitro.
Journal of Biomedical Materials Research Part A – Wiley
Published: Mar 1, 1987
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