Access the full text.
Sign up today, get DeepDyve free for 14 days.
A. Cascos (1967)
Holt‐Oram SyndromeActa Pædiatrica, 56
R. Massumi, D. Nutter (1966)
The Syndrome of Familial Defects of Heart and Upper Extremities (Holt‐Oram Syndrome)Circulation, 34
L. Holmes (1965)
CONGENITAL HEART DISEASE AND UPPER-EXTREMITY DEFORMITIES: A REPORT OF TWO FAMILIES.The New England journal of medicine, 272
R. Kaufman, D. Rimoin, W. Mcalister, A. Hartmann (1974)
Variable expression of the Holt-Oram syndrome.American journal of diseases of children, 127 1
(1966)
Syndrome of 267-276
Ann Smith, Ann Smith, George Sack, George Taylor, George Taylor (1979)
Holt-Oram syndrome.The Journal of pediatrics, 95 4
D. Krikler, B. Zilberg, A. Carter (1969)
Upper limb-cardiovascular syndrome.South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 43 29
H. Walter, A. Frank, C. Kambhu (1974)
[The Holt-Oram syndrome].Zeitschrift fur Kardiologie, 63 1
D. Ashby, J. Chadha, C. Henderson (1969)
Associated skeletal and cardiac abnormalities: the Holt-Oram syndrome.The Quarterly journal of medicine, 38 151
M. Rybak, K. Kozłowski, A. Kleczkowska, J. Lewandowska, J. Sokołowski, E. Sołtysik-Wilk (1971)
Holt-Oram syndrome associated with ectromelia and chromosomal aberrations.American journal of diseases of children, 121 6
C. Chang (1967)
Holt-oram syndrome.Radiology, 88 3
E. Kuhn, J. Schaaf, A. Wagner (1963)
Primary Pulmonary Hypertension, Congenital Heart Disease and Skeletal Anomalies in Three GenerationsJapanese Heart Journal, 4
A. Poznanski, J. Gall, A. Stern (1970)
Skeletal manifestations of the Holt-Oram syndrome.Radiology, 94 1
M. Holt, S. Oram (1960)
FAMILIAL HEART DISEASE WITH SKELETAL MALFORMATIONSBritish Heart Journal, 22
Poznanski (1972)
Objective evaluation of the hand in the Holt-Oram syndromeBirth Defects, 8
Letts (1976)
Upper limb-cardiovascular syndrome (Holt-Oram)Clin. Orthoped., 116
W. Pruzanski (1964)
FAMILIAL CONGENITAL MALFORMATIONS OF THE HEART AND UPPER LIMBS. A SYNDROME OF HOLT-ORAM.Cardiologia, 45
K. Lewis, R. Bruce, D. Baum, A. Motulsky (1965)
The upper limb-cardiovascular syndrome. An autosomal dominant genetic effect on embryogenesis.JAMA, 193 13
J. Gall, M. Aaron, Stern, M. Cohen, M. Adams (1966)
Holt-Oram syndrome: clinical and genetic study of a large family.American journal of human genetics, 18 2
P. Zeterqvist (1963)
The syndrome of familial atrial septal defect, heart arrhythmia and hand malformation (Holt-Oram) in mother and son.Acta paediatrica, 52
V. McKusick (1961)
Medical genetics 1960Journal of Chronic Diseases, 14
Marvin Miller, J. Hall (1978)
POSSIBLE MATERNAL EFFECT ON SEVERITY OF NEUROFIBROMATOSISThe Lancet, 312
Walter (1974)
Das Holt-Oram syndromeZ. Kardiol., 63
(1970)
Syndrome de Holt - Oram et malformations des mains associkes a une cardiopathie congknital
Mark (1969)
Familial and non-familial congenital abnormalities of the heart and upper extremities: A model for genetic counsellingIsrael. J. med. Sci., 5
P. Zetterqvist (1963)
The Syndrome of Familial Atrial Septal Defect, Heart Arrhythmia and Hand Malformation (Holt‐Oram) in Mother and SonActa Pædiatrica, 52
Holt-Oram syndrome is an autosomal dominant disorder with variable expression. From a review of published pedigree data and of a family reported here, we have found that penetrance is 100 % if appropriate studies, including wrist radiographs, are performed. There does not appear to be a significant maternal effect on the severity of expression in affected offspring.
Clinical Genetics – Wiley
Published: Feb 1, 1982
Keywords: Hand-heart; Holt-Oram syndrome
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.