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- Publisher
- Wiley
- Copyright
- Copyright © 2008 Wiley Periodicals, Inc.
- ISSN
- 0006-3592
- eISSN
- 1097-0290
- DOI
- 10.1002/bit.21952
- pmid
- 18512259
- Publisher site
- See Article on Publisher Site
Abstract
Boron nitride nanotubes (BNNTs) have unique physical properties, which can be exploited in the biomedical field. Hence, the surprising lack of reported studies on their biocompatibility and interactions with living cells, addressed by the present paper which deals the results of such an investigation based on 72 h culture of human neuroblastoma cell line (SH‐SY5Y) in the presence of an aqueous suspension of polyethyleneimine (PEI)‐coated BNNTs. BNNTs conjugated with fluorescent markers (quantum dots) are employed to enable tracking of their uptake by living cells. The results demonstrate good cytocompatibility together with unequivocal BNNT cellular uptake by an energy‐dependent endocytic process. Biotechnol. Bioeng. 2008;101: 850–858. © 2008 Wiley Periodicals, Inc.
Journal
Biotechnology and Bioengineering – Wiley
Published: Nov 1, 2008