Access the full text.
Sign up today, get DeepDyve free for 14 days.
J. Pollard, E. Stanley (1996)
Pleiotropic Roles for CSF-1 in Development Defined by the Mouse Mutation Osteopetrotic, 4
E. Lin, Andrew Nguyen, R. Russell, J. Pollard (2001)
Colony-Stimulating Factor 1 Promotes Progression of Mammary Tumors to MalignancyThe Journal of Experimental Medicine, 193
P. Roth, E. Stanley (1996)
Colony stimulating factor‐1 expression is developmentally regulated in the mouseJournal of Leukocyte Biology, 59
A. Borycki, M. Guillier, M. Leibovitch, S. Leibovitch (1992)
Molecular Cloning of CSF-1 Receptor from Rat Myoblasts. Sequence Analysis and Regulation During MyogenesisGrowth Factors Journal, 6
V. Gouon-Evans, E. Lin, J. Pollard (2002)
Requirement of macrophages and eosinophils and their cytokines/chemokines for mammary gland developmentBreast Cancer Research : BCR, 4
M. Lewandoski, G. Martin (1997)
Cre–mediated chromosome loss in miceNature Genetics, 17
Harriet Smith, P. Anderson, D. Kuo, G. Goldberg, C. DeVictoria, C. Boocock, Joan Jones, C. Runowicz, E. Stanley, J. Pollard (1995)
The role of colony-stimulating factor 1 and its receptor in the etiopathogenesis of endometrial adenocarcinoma.Clinical cancer research : an official journal of the American Association for Cancer Research, 1 3
I. Guleria, J. Pollard (2001)
Aberrant Macrophage and Neutrophil Population Dynamics and Impaired Th1 Response to Listeria monocytogenesin Colony-Stimulating Factor 1-Deficient MiceInfection and Immunity, 69
R. Arceci, S. Pampfer, J. Pollard (1992)
Expression of CSF-1/c-fms and SF/c-kit mRNA during preimplantation mouse development.Developmental biology, 151 1
E. Ioffe, P. Stanley (1994)
Mice lacking N-acetylglucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydrates.Proceedings of the National Academy of Sciences of the United States of America, 91
E. Sapi, B. Kacinski (1999)
The role of CSF-1 in normal and neoplastic breast physiology.Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine, 220 1
I. Guleria, J. Pollard (2000)
The trophoblast is a component of the innate immune system during pregnancyNature Medicine, 6
W. Edelmann, P. Cohen, M. Kane, K. Lau, B. Morrow, S. Bennett, A. Umar, T. Kunkel, G. Cattoretti, R. Chaganti, J. Pollard, R. Kolodner, R. Kucherlapati (1996)
Meiotic Pachytene Arrest in MLH1-Deficient MiceCell, 85
R. Tushinski, I. Oliver, L. Guilbert, P. Tynan, J. Warner, E. Stanley (1982)
Survival of mononuclear phagocytes depends on a lineage-specific growth factor that the differentiated cells selectively destroyCell, 28
A. Balmain, J. Barrett, H. Moses, S. Scholl, P. Crocker, R. Tang, P. Pouillart, J. Pollard (1993)
Is colony‐stimulating factor‐1 a key mediator of breast cancer invasion and metastasis?Molecular Carcinogenesis, 7
A. Hampe, B. Shamoon, M. Gobet, C. Sherr, F. Galibert (1989)
Nucleotide sequence and structural organization of the human FMS proto-oncogene.Oncogene research, 4 1
C. Branda, S. Dymecki (2004)
Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice.Developmental cell, 6 1
Juliette Gardner (1985)
GenesisDramatherapy, 9
J. Pollard, Melissa Dominguez, S. Mocci, Paula, E., Cohen, Richard Stanley (1997)
Effect of the colony-stimulating factor-1 null mutation, osteopetrotic (csfm(op)), on the distribution of macrophages in the male mouse reproductive tract.Biology of reproduction, 56 5
R. Teitelbaum, W. Schubert, L. Gunther, Y. Kress, F. Macaluso, J. Pollard, D. Mcmurray, B. Bloom (1999)
The M cell as a portal of entry to the lung for the bacterial pathogen Mycobacterium tuberculosis.Immunity, 10 6
J. Pollard (1997)
Role of colony‐stimulating factor‐1 in reproduction and developmentMolecular Reproduction and Development, 46
W. Wiktor-Jedrzejczak, E. Urbanowska, S. Aukerman, J. Pollard, E. Stanley, P. Ralph, A. Ansari, K. Sell, M. Szperl (1991)
Correction by CSF-1 of defects in the osteopetrotic op/op mouse suggests local, developmental, and humoral requirements for this growth factor.Experimental hematology, 19 10
W. Wiktor-Jedrzejczak, A. Bartocci, A. Ferrante, A. Ahmed-Ansari, K. Sell, J. Pollard, E. Stanley (1990)
Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse.Proceedings of the National Academy of Sciences of the United States of America, 87
V. Gouon-Evans, M. Rothenberg, J. Pollard (2000)
Postnatal mammary gland development requires macrophages and eosinophils.Development, 127 11
M. Cecchini, M. Dominguez, S. Mocci, A. Wetterwald, R. Felix, H. Fleisch, O. Chisholm, W. Hofstetter, J. Pollard, E. Stanley (1994)
Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse.Development, 120 6
Robert Arceci, Frances SHANAHANt, E. STANLEYt, Jeffrey POLLARDtf (1989)
Temporal expression and location of colony-stimulating factor 1 (CSF-1) and its receptor in the female reproductive tract are consistent with CSF-1-regulated placental development.Proceedings of the National Academy of Sciences of the United States of America, 86 22
(1983)
Mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80. Identification of resident macrophages in renal medullary and cortical interstitium and the juxtaglomerular complexThe Journal of Experimental Medicine, 157
Robert Sjin, K. Krishnaraju, B. Hoffman, D. Liebermann (2002)
Transcriptional regulation of myeloid differentiation primary response (MyD) genes during myeloid differentiation is mediated by nuclear factor Y.Blood, 100 1
Wei Tong, J. Pollard (1999)
Progesterone Inhibits Estrogen-Induced Cyclin D1 and cdk4 Nuclear Translocation, Cyclin E- and Cyclin A-cdk2 Kinase Activation, and Cell Proliferation in Uterine Epithelial Cells in MiceMolecular and Cellular Biology, 19
A. Borycki, M. Guillier, M. Leibovitch, S. Leibovitch (1992)
Molecular cloning of CSF-1 receptor from rat myoblasts. Sequence analysis and regulation during myogenesis.Growth factors, 6 3
CONDITIONAL ALLELE OF THE Csf1r
Sarah Webb, Jeffrey Pollard, Gareth Jones (1996)
Direct observation and quantification of macrophage chemoattraction to the growth factor CSF-1.Journal of cell science, 109 ( Pt 4)
Gregory Ryan, Xu-ming Dai, Melissa Dominguez, Wei Tong, F. Chuan, Orin Chisholm, Robert Russell, Jeffrey Pollard, E. Stanley (2001)
Rescue of the colony-stimulating factor 1 (CSF-1)-nullizygous mouse (Csf1(op)/Csf1(op)) phenotype with a CSF-1 transgene and identification of sites of local CSF-1 synthesis.Blood, 98 1
X Dai, GR Ryan, AJ Hapel, MG Dominguez, RG Russell, S Kapp, V Sylvestre, ER Stanley (2002)
Targeted disruption of the mouse CSF‐1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies and reproductive defectsBlood, 99
W. Edelmann, Kan Yang, A. Umar, J. Heyer, K. Lau, K. Fan, W. Liedtke, P. Cohen, M. Kane, J. Lipford, Nianjun Yu, G. Crouse, J. Pollard, T. Kunkel, M. Lipkin, R. Kolodner, R. Kucherlapati (1997)
Mutation in the Mismatch Repair Gene Msh6 Causes Cancer SusceptibilityCell, 91
Colony stimulating factor‐1 (CSF‐1) is the primary regulator of the mononuclear phagocytic lineage acting through its transmembrane tyrosine kinase receptor, CSF‐1R, that is the product of the c‐fms proto‐oncogene. Null mutations in either the ligand or the receptor genes result in a severe osteopetrosis as well as a number of other phenotypes, including reproductive defects and perturbations in organ development. The CSF‐1R is also expressed in oocytes, myoblast progenitors, decidual, and trophoblastic cells. To distinguish cell type specific phenotypes, we have created a conditional allele of the Csf1r by placing LoxP sites around Exon 5 of the Csf1r gene in mice. Excision of this floxed sequence results in a null allele that in the homozygous state gives a phenotype indistinguishable of the complete Csf1r null mutant mouse. This conditional allele will prove extremely valuable to study the spatial and temporal roles of CSF‐1R. genesis 44:328–335, 2006. © 2006 Wiley‐Liss, Inc.
Genesis: the Journal of Genetics and Development – Wiley
Published: Jul 1, 2006
Keywords: ; ; ;
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.