The Center for the Evaluation of Risks to Human Reproduction (CERHR) NTP‐CERHR Report on the Reproductive and Developmental Toxicity of Bisphenol A shows evidence of high quality scholarship, thorough evaluation and careful consideration of the very large body of published material available for bisphenol A (BPA). Although some (Taylor et al., 2008 ) have criticized the CERHR for its content, the CERHR report remains particularly valuable in human health risk assessment as “the authors identified the advantages and limitations of each report included in that review” (Willhite et al., 2008 ). The CERHR report and related reviews (Goodman et al., 2006 2008 ) point out limitations in the BPA database, despite the abundance of pharmacologic and toxicologic information on BPA. Nonetheless, there are substantial difficulties associated with the NIEHS ( 2007 ) risk communication conclusions that stem from the CERHR report. On the question of BPA hazard to human reproductive outcome, the NIEHS ( 2007 ) concluded: “What is the bottom line? Possibly . Although there is no direct evidence that exposure of people to bisphenol A adversely affects reproduction and development, studies with laboratory rodents show that exposure to high dose levels of bisphenol A during pregnancy
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Commentary
Willhite, Calvin C.
Follow Birth Defects Research Part B
, Volume 83 (3)
Wiley – Jun 1, 2008
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