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J. Jackson, V. Edwards (1975)
Kinetics of substrate inhibition of exponential yeast growthBiotechnology and Bioengineering, 17
N. Nishio, Y. Tsuchiya, M. Hayashi, S. Nagai (1977)
A Fed-Batch Culture of Methanol-utilizing Bacteria with pH Stat : Studies on Methanol Metabolism(VI) :Journal of Fermentation Technology, 55
W. Wernau, C. Wilke (1973)
New method for evaluation of dissolved oxygen probe response for KLa determinationBiotechnology and Bioengineering, 15
(1973)
Pirt, Principles of Microbes and Cell Cultivation (Wiley
T. Yamane, S. Hirano (1977)
Semi-batch Culture of Microorganisms with Constant Feed of Substrate : A Methematical Simulation : Kinetic Studies on Fed-batch Cultures(III)Journal of Fermentation Technology, 55
T. Waki, K. Suga, K. Ichikawa (1981)
PRODUCTION OF CELLULASE IN FED-BATCH CULTURE
T. Yamane, Tatsuo Kume, E. Sada, T. Takamatsu (1977)
A Simple Optimization Technique for Fed-batch Culture : Kinetic Studies on Fed-batch Cultures (VI)Journal of Fermentation Technology, 55
(1975)
Automatic Constant - Value Control of Fed - Substrate Concentration in Semi - Batch Culture
S. Aiba, S. Nagai, Y. Nishizawa (1976)
Fed batch culture of Saccharomyces cerevisiae: A perspective of computer control to enhance the productivity in baker's yeast cultivationBiotechnology and Bioengineering, 18
Automatic Control of Fed-Batch Culture for Single Cell Protein
T. Yano, Takeshi Kobayashi, S. Shimizu (1978)
Fed-batch Culture of Methanol-utilizing Bacterium with DO-stat :Journal of Fermentation Technology, 56
Henry Lim (1976)
On fed‐batch hydrocarbon fermentationBiotechnology and Bioengineering, 18
10.1002/bit.260230709.abs Candida utilis was cultivated in a 5‐liter jar fermentor using ethanol as sole carbon source. Control of ethanol in the cultivation broth was performed by using an ethanol vapor monitoring instrument and an oxygen electrode coupled with two control circuits. By setting upper and lower bounds according to the predetermined conditions, a signal from a gas monitoring sensor switched the lower or higher bound relay governing the actuating or switch‐off of the motor; this maintained a proper concentration of ethanol in the cultivation of ethanol in the system. The growth of cells was found to be satisfactory. Cell concentration reached 64 g/liter during a 20‐hr cultivation. As the results of comparative experiments, the control mode using the gas monitoring instrument was found to be superior to that using dissolved oxygen as a controlling signal, especially at high cell concentration.
Biotechnology and Bioengineering – Wiley
Published: Jul 1, 1981
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