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Health Sciences BAKSI,~AMARENDRA N., ALEXER D. KENNY. Vi- adaptive increase in the efficiency of absorption tamin D metabolism in aged Japanese quail: ary by the intestine (20,23) to an increase in 1,25(OH)zDs estrogeneffects. Am. J. Physiol. 241 (Endocrinol. Met&. production (4, 5, 15, 21). Ribovich DeLuca (25) 4): E275-E280, 1981.-The influence of estrogen treatment Omdahl DeLuca (22) have shown that 1,25(OH)zDs (estradiol benzoate, 1 mg/kg daily for 5 days) on the in vitro may be responsible for this adaptive phenomenon in renal metabolism of 25-[SH]hydroxyvitamin Da has been studyoung rats. In addition, parathyroid hormone has been ied in young adult (8-wk-old) aged (108-wk-old) female implicated in the adaptive response to depletion, male Japanese quail maintained either on a normal but its precise role is-not completely understood (22, 25, or on a low- for 4 wk. It is concluded that 26). Although it is known that the adaptive response in senescence leads to reduced production of 1,2&dihydroxyvitamin Da [ 1,25(OH)2D3] in untreated birds of both sexes intestinal absorption to deprivation deunder both ary conditions. Nevertheless, the renal vitamin clines with age (19), there is little information on the D-endocrine system in aged birds has the capacity, when stiminterrelationships between
AJP - Endocrinology and Metabolism – The American Physiological Society
Published: Oct 1, 1981
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