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Rubinsky. in freezing and anomalies Laboratory, Department of Mechanical Berkeley, California 94720 s. Engineering, Arav, Amir, and Boris and anomalies Physiol. 267 (Regulatory Integrative Am. J. Comp. Physiol. 36): R1646-Rl652, 1994.-Whave developed a new device that measures freezing and melting s in nanoliter volume samples and can be used as a âfreezing point â with a resolution many orders of magnitude greater than that of existing freezing point s. Using this device we found anomalies in the depression of the freezing and thermal hysteresis in aqueous solutions of hydrophilic amino acids, polyamino acids, and k&ins. These anomalies would not have been possible to detect with currently used technology. The compounds that produce anomalies in freezing were reported in the literature as having the ability to bind to cell membranes. This suggests a relation between a moleculeâs ability to bind to cell membranes and its anomalous freezing depression. The new freezing point and our results could be important for studying and understanding organic molecules and their interaction with membranes and water. freezing point ; lality of organic molecules thermal hysteresis proteins; osmo- THE FREEZING depressionofasolutionisa thermodynamic property indicative of the solvent free energy (22) and is considered colligative because
AJP - Regulatory, Integrative and Comparative Physiology – The American Physiological Society
Published: Dec 1, 1994
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