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PAUL A. Department Department Physiulugy Pediatrics, and Huustun P&natal Nutrition Laboratory, University Texas Medical School, Houston, Texas 77030 LENARD M., SHARONS. PAUL A. AND FRANK KMORRISS, JR. tissueand serum gustr concentrations LIZfetal and neonatal . Am. J. Physiol. 241 (Gastrotest. Liver Physiol 4): G235-G241, 1981.-We vestigated the peratal ontogenic changes m ove serum and tissue gastr concentration. Fetal and maternal serum gastr levels serums obtaed from dwellg catheters the fetal and maternal circulations and tissue gastr levels were assessed by radioimmunoassay and immunohistochemistry. Fetal serum gastr concentration was undetectable until the 107th day gestation and significantly creased to levels surpassg maternal values. Neonatal serum hormone concentration contued to rise, reachg a peak durg the 4th postnatal wk and decreasg after the 4th wk cocident with weang. Maternal serum gastr concentration did not vary durg pregnancy and did not correlate with fetal serum gastr levels. Fetal abomasal and duodenal gastr concentrations and abomasal G-cell number creased parallel with the developmental alterations fetal serum hormone levels durg gestation. The developmental crease abomasal gastr concentration was not associated with a shift the molecular form the hormone, These fdgs support the hypothesis that circulatg gastr the fetus is fetal orig. abomasum; G
AJP - Gastrointestinal and Liver Physiology – The American Physiological Society
Published: Sep 1, 1981
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