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METHODS THE ING STATE produces a decrease in both minute tidal volume (1, 4, 9, 26). In addition, measures of the chemical control of respiration (hypoxic hypercapnic ventilatory responses) are also reduced compared with wakefulness (2,3,7,8). Why this occurs is the subject of considerable speculation may well be multifactorial. could decrease in ing individuals simply as a product of falling metabolic rate (6, 37), but this is not the entire answer inasmuch as PCO~ levels increase (1, 8, 13), indicating a larger decrease in alveolar than CO2 production. Some would argue that this is likely to be a product of decreasing central nervous system sensitivity to the normal stimuli that maintain (e.g., hypoxia, hypercapnia, CO, production). An alternative explanation is that air0161-7567/86 $1.50 Copyright Eighteen normal healthy males females were studied. Their physical characteristics are given in Table I. The two older women were postmenopausal whereas all other females had normal menses historically. No effort was made to study these women at any particular point in the menstrual cycle. None of the subjects were currently taking medication, smoking cigarettes, or had any complaints. Snorers were not excluded, snoring was assessedqualitatively on the night of the study by a
Journal of Applied Physiology – The American Physiological Society
Published: Oct 1, 1986
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