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New Insights Into Molecular Players Involved in Neurotransmitter Release

New Insights Into Molecular Players Involved in Neurotransmitter Release The strength of a synapse can profoundly influence network function. How this strength is set at the molecular level is a key question in neuroscience. Here, we review a simple model of neurotransmission that serves as a convenient framework to discuss recent studies on RIM and synaptotagmin. Footnotes This work was supported by funds from the National Institutes of Health (NS-036942, MH-085783) to T. A. Ryan and the David Rockefeller Graduate Program of the Rockefeller University (P. Ariel). No conflicts of interest, financial or otherwise, are declared by the author(s). Author contributions: P.A. and T.A.R. conception and design of research; P.A. performed experiments; P.A. analyzed data; P.A. and T.A.R. interpreted results of experiments; P.A. prepared figures; P.A. drafted the manuscript; P.A. and T.A.R. edited and revised the manuscript; P.A. and T.A.R. approved the final version of the manuscript. ©2012 Int. Union Physiol. Sci./Am. Physiol. Soc. « Previous | Next Article » Table of Contents This Article doi: 10.​1152/​physiol.​00035.​2011 Physiology February 2012 vol. 27 no. 1 15-24 » Abstract Free Full Text Free to you Full Text (PDF) Free to you Classifications Review Services Email this article to a friend Alert me when this article is cited Alert me if a correction is posted Similar articles in this journal Similar articles in Web of Science Download to citation manager Citing Articles Load citing article information Citing articles via Web of Science Google Scholar Articles by Ariel, P. Articles by Ryan, T. A. PubMed Articles by Ariel, P. Articles by Ryan, T. A. Related Content Load related web page information Current Issue February 2012, 27 (1) Alert me to new issues of Physiology About the Journal Information for Authors Submit a Manuscript Ethical Policies AuthorChoice PubMed Central Policy Reprints and Permissions Advertising Press Copyright © 2012 the American Physiological Society Print ISSN: 1548-9213 Online ISSN: 1548-9221 var gaJsHost = (("https:" == document.location.protocol) ? "https://ssl." : "http://www."); document.write(unescape("%3Cscript src='" + gaJsHost + "google-analytics.com/ga.js' type='text/javascript'%3E%3C/script%3E")); var pageTracker = _gat._getTracker("UA-2924550-1"); pageTracker._trackPageview(); http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Physiology The American Physiological Society

New Insights Into Molecular Players Involved in Neurotransmitter Release

Ariel, Pablo; Ryan, Timothy A.
Physiology , Volume 27 (1): 15 – Feb 1, 2012
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References (78)

Publisher
The American Physiological Society
Copyright
Copyright © 2012 the American Physiological Society
ISSN
1548-9213
eISSN
1548-9221
DOI
10.1152/physiol.00035.2011
pmid
22311967
Publisher site
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Abstract

The strength of a synapse can profoundly influence network function. How this strength is set at the molecular level is a key question in neuroscience. Here, we review a simple model of neurotransmission that serves as a convenient framework to discuss recent studies on RIM and synaptotagmin. Footnotes This work was supported by funds from the National Institutes of Health (NS-036942, MH-085783) to T. A. Ryan and the David Rockefeller Graduate Program of the Rockefeller University (P. Ariel). No conflicts of interest, financial or otherwise, are declared by the author(s). Author contributions: P.A. and T.A.R. conception and design of research; P.A. performed experiments; P.A. analyzed data; P.A. and T.A.R. interpreted results of experiments; P.A. prepared figures; P.A. drafted the manuscript; P.A. and T.A.R. edited and revised the manuscript; P.A. and T.A.R. approved the final version of the manuscript. ©2012 Int. Union Physiol. Sci./Am. Physiol. Soc. « Previous | Next Article » Table of Contents This Article doi: 10.​1152/​physiol.​00035.​2011 Physiology February 2012 vol. 27 no. 1 15-24 » Abstract Free Full Text Free to you Full Text (PDF) Free to you Classifications Review Services Email this article to a friend Alert me when this article is cited Alert me if a correction is posted Similar articles in this journal Similar articles in Web of Science Download to citation manager Citing Articles Load citing article information Citing articles via Web of Science Google Scholar Articles by Ariel, P. Articles by Ryan, T. A. PubMed Articles by Ariel, P. Articles by Ryan, T. A. Related Content Load related web page information Current Issue February 2012, 27 (1) Alert me to new issues of Physiology About the Journal Information for Authors Submit a Manuscript Ethical Policies AuthorChoice PubMed Central Policy Reprints and Permissions Advertising Press Copyright © 2012 the American Physiological Society Print ISSN: 1548-9213 Online ISSN: 1548-9221 var gaJsHost = (("https:" == document.location.protocol) ? "https://ssl." : "http://www."); document.write(unescape("%3Cscript src='" + gaJsHost + "google-analytics.com/ga.js' type='text/javascript'%3E%3C/script%3E")); var pageTracker = _gat._getTracker("UA-2924550-1"); pageTracker._trackPageview();

Journal

Physiology – The American Physiological Society

Published: Feb 1, 2012

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