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R274 0363-6119/S $1.50 Copyright @I 1985 the American Physiological Society MKEY R275 2-wk run in 24 of the 69 experiments. If the mkey was entrained, it should begin free-running from a phase predicted by the phase of the previous LD cycle. Thirteen 4-wk experiments were cducted at the borders of the range of entrainment. Before the end of these experiments, the data were analyzed, if entrainment persisted the mkey was released into DD for lo-14 days. These DD data were also subjected to phase analysis. RESULTS wk. After eliminating days l-5 as transients, sine waves were fitted to successive 24-h segments of data. A regressi line was fitted through the peaks of the sine waves the y-intercept calculated. After a 1-wk return to LD l2:12, the experiment was repeated with e differencea l-h pulse of (600 lx) was given at a specific circadian time during the first 24 h of DD. The circadian time scale is a 24-h scale with 0 representing s 12 representing s off. The difference between the pulse y-intercept the ctrol y-intercept was the phase shift due to the 1-h pulse of given the 1st day of DD. Each animal served as its own
AJP - Regulatory, Integrative and Comparative Physiology – The American Physiological Society
Published: Aug 1, 1985
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