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Heesch, Cheryl M., and Kirk W. Barron. Is there a central nervous system to resettg rats? Am. J. Physiol. 262 (Heart Ci. Physiol. 31): H503H510, 1992.-This study was designed to evaluate a possible central nervous system () to resettg. ne arterial baroreceptor-denervated, chloraloseurethan-anesthetized rats, a control (C) aortic nerve stimulation curve (3-5 V, 1 ms, O-64 Hz) was obtaed. Next, a constant âbaroreceptorâ put was delivered to the (left aortic nerve stimulation, 10 m, 10.2 t 1.5 Hz). With the fit 13 s of aortic nerve stimulation, maximum hibition of lumbar sympathetic nerve activity (LSNA) was 60 t 7.8% of basele and at 1 m it creased to 68 + 5.6% of basele. At the end of the lo-m aortic nerve stimulation, LSNA was not different from the response at 1 m (68 & 5.6% = 74 t 4.1%). Immediately after the constant stimulation (with 30 s), a test or reset () curve was obtaed (O-64 Hz). A recovery () curve was obtaed lo-20 m later. The slope of the lear portion of the curve and the stimulation frequency that produced 50% maximum hibition (E&J were compared among the three curves (C, , ,) and no significant differences
AJP - Heart and Circulatory Physiology – The American Physiological Society
Published: Feb 1, 1992
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