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MARY ELIZABETH Institute Bethesda, REID 77. S. Public Health Service, Division of Chemotherapy, Yational of Health, Md. A better understanding of the physiological effect,s of vitamins in plants and in animals is a goal t,oward which a number of different lines of investigation are now being directed. Some insight has been gained concerning the mode of action of several of these substancesin animals but comparatively little is known of t)heir functions in plants. It has been demonstrated that several members of the vitamin B complex participate in respiratorv processesand because of it,s reducing action, it has been suggested that ascorbic acid also is concerned in respiration. There is as yet, however, no considerable amount of evidence clearly indicating such a relationship in intact tissues. Ascorbic acid is known to be involved in tlhe synthesis of collagen and reticulin, carbohydrate-containing sclero-proteins found in bones and connective tissue and in smaller amounts in other animal tissues. These frame-work proteins all presumably contain small amounts of carbohydrates and function in animals in much the same way as do the anhydrides of hexoses and pentoses in the cellulose, lignin, pentosans, etc., in plants. It has not been discovered whether ascorbic acid is
Physiological Reviews – The American Physiological Society
Published: Jan 1, 1943
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