Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Gastric emptying and secretion in the rhesus monkey

Gastric emptying and secretion in the rhesus monkey The volume and composition of the gastric contents as well as the rates of gastric emptying and secretion were determined simultaneously in conscious chair-adapted monkeys. These determinations were made during fasting and after a liquid meal, thereby allowing studies of the physiologic variables which regulate gastric emptying and gastric secretion. Administration of a water meal is followed by a complex pattern of changes in rates of secretion as well as the fractional rate of emptying. During administration of a 100-ml water meal (pH 7.4), intragastric volume increased while acid concentration decreased; both then returned to fasting values 50 min later. The fractional rate of emptying increased fivefold during administration of the water meal, returned to basal values after 30 min, and then increased again, indicating that gastric emptying cannot be characterized as a simple first-order process with a constant coefficient. The pattern of the change in the rate of water secretion was similar to that for fractional gastric emptying. In contrast, after the meal, gastric acid secretion increased steadily and did not become maximal until 20 min. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png AJP - Gastrointestinal and Liver Physiology The American Physiological Society

Gastric emptying and secretion in the rhesus monkey

Download PDF
7 pages

Loading next page...
 
/lp/the-american-physiological-society/gastric-emptying-and-secretion-in-the-rhesus-monkey-1wdBlt0nRl

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
The American Physiological Society
Copyright
Copyright © 1977 the American Physiological Society
ISSN
0193-1857
eISSN
1522-1547
Publisher site
See Article on Publisher Site

Abstract

The volume and composition of the gastric contents as well as the rates of gastric emptying and secretion were determined simultaneously in conscious chair-adapted monkeys. These determinations were made during fasting and after a liquid meal, thereby allowing studies of the physiologic variables which regulate gastric emptying and gastric secretion. Administration of a water meal is followed by a complex pattern of changes in rates of secretion as well as the fractional rate of emptying. During administration of a 100-ml water meal (pH 7.4), intragastric volume increased while acid concentration decreased; both then returned to fasting values 50 min later. The fractional rate of emptying increased fivefold during administration of the water meal, returned to basal values after 30 min, and then increased again, indicating that gastric emptying cannot be characterized as a simple first-order process with a constant coefficient. The pattern of the change in the rate of water secretion was similar to that for fractional gastric emptying. In contrast, after the meal, gastric acid secretion increased steadily and did not become maximal until 20 min.

Journal

AJP - Gastrointestinal and Liver Physiology – The American Physiological Society

Published: Feb 1, 1977

There are no references for this article.