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H. C. J. H. S. S. Laboratory of Cellular Dynamics Departments of Physiology Medicine, University of California, San Francisco, Department of Medicine, San Francisco General Hospital, San Francisco, California 94143 H.C., J.H. S.S..FOO~, by the pancreas. Am. J. Physiol. 243 (Gastrointest. Liver Physiol. 6): G304-G312, 1982.-Previous studies have reported that of extracts from rats fed different meals into the celiac artery of recipient rats elicited the of related pancreatic s. We have been unable to reproduce the -specific increases in the average output of particular s that were observed but did find changes similar in direction, although not magnitude, to those reported previously. The outputs of amylase trypsinogen were compared by plotting individual data points performing a regression analysis on them. The of extracts from lactalbumin hydrolysate-fed rats led to trypsinogen being favored over that of amylase vice versa for extracts from rats fed a glucose meal. In addition, it was found that cholecystokinin-pancreozymin produced a dramatic nonparallel transport of these two s with amylase being augmented to a greater degree than trypsinogen . The relation between their outputs was curvilinear, i.e., the amylase dominance of became more pronounced as overall output (not dose of hormone) increased. Thus,
AJP - Gastrointestinal and Liver Physiology – The American Physiological Society
Published: Oct 1, 1982
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