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PART OF From the Physiological Laboratory Although studies of capillary contractility extend back for a period of fifty years almost to the time of the discovery of vasomotor nerves, and although the profound significance of the blood stream in the capillary areas for tissue nutrition was recognized at an even earlier period, capillary function is given scant if any consideration in discussion of vascular reactions today. The simple hypothesis of vascular control by means of functional activity on the part of the arterioles has been adequate to explain experimental results. Yet in recent years a considerable amount of evidence has been collected which goes to show that this conception is inadequate. First it developed that the venous bed may participate independently of the arterial function, and more recently it appears that the capillary area likewise plays a significant role in these reactions. This evidence has not as yet been assimilated to the point of modifying the older hypotheses. Indeed it constitutes little more than ground work: nevertheless, when gathered together, it presents a mass of data which cannot well be neglected. Basing deductions upon this newer evidence, we may well expect the future to rapidly broaden our conceptions
Physiological Reviews – The American Physiological Society
Published: Jan 1, 1921
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