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EVIDENCE OF FUNCTIONAL ACTIVITY ON THE PART OF THE CAPILLARIES AND VENULES

EVIDENCE OF FUNCTIONAL ACTIVITY ON THE PART OF THE CAPILLARIES AND VENULES PART OF From the Physiological Laboratory Although studies of capillary contractility extend back for a period of fifty years almost to the time of the discovery of vasomotor nerves, and although the profound significance of the blood stream in the capillary areas for tissue nutrition was recognized at an even earlier period, capillary function is given scant if any consideration in discussion of vascular reactions today. The simple hypothesis of vascular control by means of functional activity on the part of the arterioles has been adequate to explain experimental results. Yet in recent years a considerable amount of evidence has been collected which goes to show that this conception is inadequate. First it developed that the venous bed may participate independently of the arterial function, and more recently it appears that the capillary area likewise plays a significant role in these reactions. This evidence has not as yet been assimilated to the point of modifying the older hypotheses. Indeed it constitutes little more than ground work: nevertheless, when gathered together, it presents a mass of data which cannot well be neglected. Basing deductions upon this newer evidence, we may well expect the future to rapidly broaden our conceptions http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Physiological Reviews The American Physiological Society

EVIDENCE OF FUNCTIONAL ACTIVITY ON THE PART OF THE CAPILLARIES AND VENULES

Physiological Reviews , Volume 1: 112 – Jan 1, 1921

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Publisher
The American Physiological Society
Copyright
Copyright © 1921 the American Physiological Society
ISSN
0031-9333
eISSN
1522-1210
Publisher site
See Article on Publisher Site

Abstract

PART OF From the Physiological Laboratory Although studies of capillary contractility extend back for a period of fifty years almost to the time of the discovery of vasomotor nerves, and although the profound significance of the blood stream in the capillary areas for tissue nutrition was recognized at an even earlier period, capillary function is given scant if any consideration in discussion of vascular reactions today. The simple hypothesis of vascular control by means of functional activity on the part of the arterioles has been adequate to explain experimental results. Yet in recent years a considerable amount of evidence has been collected which goes to show that this conception is inadequate. First it developed that the venous bed may participate independently of the arterial function, and more recently it appears that the capillary area likewise plays a significant role in these reactions. This evidence has not as yet been assimilated to the point of modifying the older hypotheses. Indeed it constitutes little more than ground work: nevertheless, when gathered together, it presents a mass of data which cannot well be neglected. Basing deductions upon this newer evidence, we may well expect the future to rapidly broaden our conceptions

Journal

Physiological ReviewsThe American Physiological Society

Published: Jan 1, 1921

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