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Effects of left atrial stretch in cardiac-denervated and intact conscious dogs

Effects of left atrial stretch in cardiac-denervated and intact conscious dogs , DENNIS C., HAROLD D. SCHULTZ, WARREN D. SUNDET, JEFFREY S. MAPES, AND KENNETH L. GOETZ. Effects of left and tact conscious . Am. J. Physiol. 242 (Heart Circ. Physiol. 11): H1056H1064,1982.-We monitored cardiovascular and renal function conscious with surgically denervated hearts durg two experimental procedures: 1) flation of a balloon the left atrium and 2) travascular volume expansion. The results obtaed were compared with results from identical experiments on sham-operated control . Left balloon flation the sham-operated produced an crease left pressure, heart rate, ure flow, and sodium excretion; central venous pressure decreased. These changes were absent the . fusion of 6% dextran isotonic sale (16% of estimated blood volume) creased the heart rate significantly the control but not the ; other hemodynamic measurements were comparable the two groups. Ure flow and sodium excretion creased significantly both the and control ; the responses did not differ significantly between the two groups. These experiments demonstrate that flation of a balloon the left atrium of a conscious dog elicits diuretic and natriuretic responses that are dependent on tact cardiac neural pathways, presumably specifically dependent on afferent neural impulses from left receptors. On the other hand, an crease circulatg blood http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png AJP - Heart and Circulatory Physiology The American Physiological Society

Effects of left atrial stretch in cardiac-denervated and intact conscious dogs

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Publisher
The American Physiological Society
Copyright
Copyright © 1982 the American Physiological Society
ISSN
0363-6135
eISSN
1522-1539
Publisher site
See Article on Publisher Site

Abstract

, DENNIS C., HAROLD D. SCHULTZ, WARREN D. SUNDET, JEFFREY S. MAPES, AND KENNETH L. GOETZ. Effects of left and tact conscious . Am. J. Physiol. 242 (Heart Circ. Physiol. 11): H1056H1064,1982.-We monitored cardiovascular and renal function conscious with surgically denervated hearts durg two experimental procedures: 1) flation of a balloon the left atrium and 2) travascular volume expansion. The results obtaed were compared with results from identical experiments on sham-operated control . Left balloon flation the sham-operated produced an crease left pressure, heart rate, ure flow, and sodium excretion; central venous pressure decreased. These changes were absent the . fusion of 6% dextran isotonic sale (16% of estimated blood volume) creased the heart rate significantly the control but not the ; other hemodynamic measurements were comparable the two groups. Ure flow and sodium excretion creased significantly both the and control ; the responses did not differ significantly between the two groups. These experiments demonstrate that flation of a balloon the left atrium of a conscious dog elicits diuretic and natriuretic responses that are dependent on tact cardiac neural pathways, presumably specifically dependent on afferent neural impulses from left receptors. On the other hand, an crease circulatg blood

Journal

AJP - Heart and Circulatory PhysiologyThe American Physiological Society

Published: Jun 1, 1982

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