Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Effect of Pulmonary Diffusing Capacity on Exercise Tolerance

Effect of Pulmonary Diffusing Capacity on Exercise Tolerance Dz$&ng Capacity on Exe&se RICHARD Medicine, H. SHEPARD. The Johns Hopkins From the Departments of Medicine University, Baltimore, Maryland and Environmental techniques for measurement of pulmonary diffusing capacity and causes of variation in different physiological and pathological states have been discussed extensively over the years (I-S), the quantitative relationships between diffusing capacity and ability to perform physical activity have not to our knowledge been adequately described. If diffusing capacity is lowered, the tension gradient between alveolar gas and pulmonary capillary blood must be larger for oxygen to cross the pulmonary membrane at a given rate. Since alveolar POT is relatively fixed, this increase in gradient is reflected for the most part in a lowering of the oxygen saturation of the blood leaving the lungs. Impairment of diffusing capacity, therefore, limits exercise tolerance by lowering the oxygen saturation of arterial blood in this manner. The relationships between diffusing capacity and oxygen saturation may be calculated in the following way. When oxygen uptake (VOW) and diffusing capacity (DoJ are known, the mean alveolo-capillary POT gradient (PA% Pc02) may be calculated from the expression LTHOUGH Figures 2 and 3 were made by choosing values of Doa and voz, calculating PAN, - http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Applied Physiology The American Physiological Society

Effect of Pulmonary Diffusing Capacity on Exercise Tolerance

Richard H. Shepard
Journal of Applied Physiology , Volume 12: 487 – May 1, 1958
Download PDF
2 pages

Loading next page...
 
/lp/the-american-physiological-society/effect-of-pulmonary-diffusing-capacity-on-exercise-tolerance-0eQGqAwGRV

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
The American Physiological Society
Copyright
Copyright © 1958 the American Physiological Society
ISSN
8750-7587
eISSN
1522-1601
Publisher site
See Article on Publisher Site

Abstract

Dz$&ng Capacity on Exe&se RICHARD Medicine, H. SHEPARD. The Johns Hopkins From the Departments of Medicine University, Baltimore, Maryland and Environmental techniques for measurement of pulmonary diffusing capacity and causes of variation in different physiological and pathological states have been discussed extensively over the years (I-S), the quantitative relationships between diffusing capacity and ability to perform physical activity have not to our knowledge been adequately described. If diffusing capacity is lowered, the tension gradient between alveolar gas and pulmonary capillary blood must be larger for oxygen to cross the pulmonary membrane at a given rate. Since alveolar POT is relatively fixed, this increase in gradient is reflected for the most part in a lowering of the oxygen saturation of the blood leaving the lungs. Impairment of diffusing capacity, therefore, limits exercise tolerance by lowering the oxygen saturation of arterial blood in this manner. The relationships between diffusing capacity and oxygen saturation may be calculated in the following way. When oxygen uptake (VOW) and diffusing capacity (DoJ are known, the mean alveolo-capillary POT gradient (PA% Pc02) may be calculated from the expression LTHOUGH Figures 2 and 3 were made by choosing values of Doa and voz, calculating PAN, -

Journal

Journal of Applied Physiology – The American Physiological Society

Published: May 1, 1958

There are no references for this article.