Access the full text.
Sign up today, get DeepDyve free for 14 days.
References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.
GREGORY D., WILLIAM J. MARK E. . Effect of forebrain lesions on response to chronic intraventricular angiotensin II. Am. J. Physiol. 244 (Regulatory Integrative Comp. Physiol. 13): R45-R50, 1983.-We previously reported that chronic (10 days) intracerebroventricular (ivt) infusion of angiotensin II (ANG II) into conscious rabbits produced a significant rise in mean arterial pressure (MAP), water intake (WI), urinary sodium excretion (U,,V), a significant fall in plasma sodium (PN~) potassium (Pk) concentrations. Urinary potassium excretion (UkV) body fluid volume were not changed significantly. In the present experiments, &n&r chronic infusions were carried out in intact rabbits in rabbits with an electrolytic lesion placed in the anteroventral third cerebral ventricle (AV3V) region. Integrity of the AV3V area is essential for normal expression of a variety of acute physiological responses to ANG II injected into the brain. In rabbits with AV3V lesions, chronic ivt infusion of ANG II did not significantly alter MAP, but WI fractional UNaV increased, PNa decreased in a er identical to that of sham-lesioned control rabbits. Plasma extracellular fluid volumes increased, body weight food intake decreased in all rabbits during ANG II infusion, but to a slightly greater extent in the AV3Vlesioned rabbits. We conclude that
AJP - Regulatory, Integrative and Comparative Physiology – The American Physiological Society
Published: Jan 1, 1983
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.