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Dietary fructose enhances intestinal fructose transport and GLUT5 expression in weaning rats

Dietary fructose enhances intestinal fructose transport and GLUT5 expression in weaning rats DEVELOPMENT, testal nutrient transporters may be classified to two categories: those that exhibit high transport rates before birth, such as the Na+dependent glucose transporter SGLTl and some amo acid transporters, and those that show high transport rates only after birth or weang, such as the fructose transporter 5 and bile acid transporters (3). The signal(s) triggerg or regulatg the appearance or enhancement of levels of any one particular transporter is not known. Genetic, hormonal, or dietary factors or a combation of more than one of these factors is very likely to be the cause(s). The timg mechanism underlyg the steep crease fructose transport rates postweang can be considered to be genetically programmed. The transport rate creases dramatically at the end of weang G446 0193-1857/97 $5.00 Copyright o 1997 or at 28 days of age pups allowed to wean normally, and at 28 days of age pups whose weang was prolonged by matag them on dry milk. These observations suggest that the timg mechanism of the testal fructose transporter is “hardwired” (29) Regardg the effect of hormones on testal transporters durg development, James et al. (16) have shown that the glucocorticoid receptor agonist dexamethasone stimulated testal Na+-dependent alane uptake http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png AJP - Gastrointestinal and Liver Physiology The American Physiological Society

Dietary fructose enhances intestinal fructose transport and GLUT5 expression in weaning rats

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Publisher
The American Physiological Society
Copyright
Copyright © 1997 the American Physiological Society
ISSN
0193-1857
eISSN
1522-1547
Publisher site
See Article on Publisher Site

Abstract

DEVELOPMENT, testal nutrient transporters may be classified to two categories: those that exhibit high transport rates before birth, such as the Na+dependent glucose transporter SGLTl and some amo acid transporters, and those that show high transport rates only after birth or weang, such as the fructose transporter 5 and bile acid transporters (3). The signal(s) triggerg or regulatg the appearance or enhancement of levels of any one particular transporter is not known. Genetic, hormonal, or dietary factors or a combation of more than one of these factors is very likely to be the cause(s). The timg mechanism underlyg the steep crease fructose transport rates postweang can be considered to be genetically programmed. The transport rate creases dramatically at the end of weang G446 0193-1857/97 $5.00 Copyright o 1997 or at 28 days of age pups allowed to wean normally, and at 28 days of age pups whose weang was prolonged by matag them on dry milk. These observations suggest that the timg mechanism of the testal fructose transporter is “hardwired” (29) Regardg the effect of hormones on testal transporters durg development, James et al. (16) have shown that the glucocorticoid receptor agonist dexamethasone stimulated testal Na+-dependent alane uptake

Journal

AJP - Gastrointestinal and Liver PhysiologyThe American Physiological Society

Published: Mar 1, 1997

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