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Barbiturate-Curare-Induced Apnea for Artificial Respiration Studies on Normal Adults. I

Barbiturate-Curare-Induced Apnea for Artificial Respiration Studies on Normal Adults. I December NUMBER Barbitzlrate-Czlrare-Indzlced Apnea for Artijciul Respiration Studies on Normal Addts, I’ MAX AND S. SADOVE, A. ARCHER S. GORDON, JOHN T. NELSON C. WY. From the Departments of Clinical Science and Surgery (Anesthesia), University of Illinois College of Medicine, Chicago, Illinois in this laboratory have evaluated artificial respiration on lower animals (r-3)) fresh corpses (4), and subjects who have voluntarily suspended respiration (5). However, in order to study the various effects of different types of manual resuscitation in living, nonbreathing human subjects, it was necessary to evolve a method, as safe as possible, to produce total apnea. For the purpose of these studies, it was desired to have subjects in a state closely resembling that of patients who might require manual artificial respiration. Such subjects should be relatively atonic and incapable of either assisting or resisting the operator. It was further desired that these subjects be asleep in order to have an amnesia for the procedure. In addition, it was necessary to have a gas-tight respiratory system in order to make exact measurements. The maintenance of a free airway and provisions for alternate methods of artificial respiration were essential. This was provided by an endotracheal tube through http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Applied Physiology The American Physiological Society

Barbiturate-Curare-Induced Apnea for Artificial Respiration Studies on Normal Adults. I

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Publisher
The American Physiological Society
Copyright
Copyright © 1951 the American Physiological Society
ISSN
8750-7587
eISSN
1522-1601
Publisher site
See Article on Publisher Site

Abstract

December NUMBER Barbitzlrate-Czlrare-Indzlced Apnea for Artijciul Respiration Studies on Normal Addts, I’ MAX AND S. SADOVE, A. ARCHER S. GORDON, JOHN T. NELSON C. WY. From the Departments of Clinical Science and Surgery (Anesthesia), University of Illinois College of Medicine, Chicago, Illinois in this laboratory have evaluated artificial respiration on lower animals (r-3)) fresh corpses (4), and subjects who have voluntarily suspended respiration (5). However, in order to study the various effects of different types of manual resuscitation in living, nonbreathing human subjects, it was necessary to evolve a method, as safe as possible, to produce total apnea. For the purpose of these studies, it was desired to have subjects in a state closely resembling that of patients who might require manual artificial respiration. Such subjects should be relatively atonic and incapable of either assisting or resisting the operator. It was further desired that these subjects be asleep in order to have an amnesia for the procedure. In addition, it was necessary to have a gas-tight respiratory system in order to make exact measurements. The maintenance of a free airway and provisions for alternate methods of artificial respiration were essential. This was provided by an endotracheal tube through

Journal

Journal of Applied PhysiologyThe American Physiological Society

Published: Dec 1, 1951

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