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Ambiguities and errors in evaluation of capillary pore sizes

Ambiguities and errors in evaluation of capillary pore sizes To the Editor: In reviewing the calculations Granger and A. E. Taylor in a recent study (5)) I a discrepancy between the curves in their Fig. (3dvs. solute radius for pores of given sizes and 2 of D. N. observed 5 of 1 their Eq. od = 16/3 (a/R)2 - 20/3 (a/R)” + 7/3 (a/R)4 - 0.354 (a/R)” (I) where 0d is the osmotic reflection coefficient, a is molecular radius, and R is pore radius. This equation is attributed to D. G. Levitt (6). Only the first two terms are given in Levitt’s paper, though the existence of more is suggested. Drake and Davis (4) give the third term. To my knowledge the fourth term has not been published before. Curves of 1 - od vs. a/R calculated from the two-term and the complete four-term versions of this equat,ion do not correspond to those shown by Granger and Taylor in their Fig. 5. The graphed curves correspond closely to a plot of only the first three terms, as given by Drake and Davis, or to plots of a variety of more elaborate expressions derived to represent the hydrodynamic interaction of spherical molecules entrained in laminar flow within a http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png AJP - Heart and Circulatory Physiology The American Physiological Society

Ambiguities and errors in evaluation of capillary pore sizes

E. M. Renkin
AJP - Heart and Circulatory Physiology , Volume 240: H145 – Jan 1, 1981
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Publisher
The American Physiological Society
Copyright
Copyright © 1981 the American Physiological Society
ISSN
0363-6135
eISSN
1522-1539
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Abstract

To the Editor: In reviewing the calculations Granger and A. E. Taylor in a recent study (5)) I a discrepancy between the curves in their Fig. (3dvs. solute radius for pores of given sizes and 2 of D. N. observed 5 of 1 their Eq. od = 16/3 (a/R)2 - 20/3 (a/R)” + 7/3 (a/R)4 - 0.354 (a/R)” (I) where 0d is the osmotic reflection coefficient, a is molecular radius, and R is pore radius. This equation is attributed to D. G. Levitt (6). Only the first two terms are given in Levitt’s paper, though the existence of more is suggested. Drake and Davis (4) give the third term. To my knowledge the fourth term has not been published before. Curves of 1 - od vs. a/R calculated from the two-term and the complete four-term versions of this equat,ion do not correspond to those shown by Granger and Taylor in their Fig. 5. The graphed curves correspond closely to a plot of only the first three terms, as given by Drake and Davis, or to plots of a variety of more elaborate expressions derived to represent the hydrodynamic interaction of spherical molecules entrained in laminar flow within a

Journal

AJP - Heart and Circulatory Physiology – The American Physiological Society

Published: Jan 1, 1981

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