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The prevalence of diabetes mellitus and an assessment of methods of detection among a community of elderly Chinese in Hong Kong

The prevalence of diabetes mellitus and an assessment of methods of detection among a community... 125 30 30 11 11 J. Woo R. Swaminathan C. Cockram C. P. Pang Y. T. Mak S. Y. Au J. Vallance-Owen Department of Medicine Prince of Wales Hospital, Chinese University of Hong Kong Shatin, NT Hong Kong Department of Chemical Pathology Prince of Wales Hospital, Chinese University of Hong Kong Shatin, NT Hong Kong Summary This study provides information on the prevalence of diabetes mellitus in a group of elderly Chinese subjects aged 60 and above living in the community in Hong Kong, and investigates the sensitivity of the urine sugar, random blood glucose, glycosylated haemoglobin, and fructosamine measurements compared to a glucose tolerance test in screening for diabetes mellitus in this population. Four hundred twenty-seven subjects aged 60 and above were studied. The National Diabetes Data Group Criteria were used for the diagnosis of diabetes. Those with a random blood glucose exceeding 12.5 mmol/l were considered diabetic, and all of these patients had glycosuria together with elevated total glycosylated haemoglobin and fractosamine concentrations. A diagnostic 75 g oral glucose tolerance test was performed on patients with one or more of the following abnormalities: glycosuria, random plasma blood glucose 7.8 mmol/l to 12.5 mmol/l, glycosylated haemoglobin 8.5%, and fructosamine 2.20 mmol/l. By these criteria, the prevalence of diabetes in this community was found to be 9.8%. An elevated random glucose greater than 11.1 mmol/l proved to be the only specific method of screening and glycosuria was found to be at least as good as fractosamine and HbA 1 . However, HbA 1 is more sensitive than random glucose, glycosuria or fructosamine in detecting impaired glucose tolerance. On the basis of this study, a higher reference range for glycosylated haemoglobin for the elderly alone is also suggested (5.74–9.34%). http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Diabetologia Springer Journals

The prevalence of diabetes mellitus and an assessment of methods of detection among a community of elderly Chinese in Hong Kong

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References (34)

Publisher
Springer Journals
Copyright
Copyright © 1987 by Springer-Verlag
Subject
Medicine & Public Health; Human Physiology; Internal Medicine; Metabolic Diseases
ISSN
0012-186X
eISSN
1432-0428
DOI
10.1007/BF00274795
Publisher site
See Article on Publisher Site

Abstract

125 30 30 11 11 J. Woo R. Swaminathan C. Cockram C. P. Pang Y. T. Mak S. Y. Au J. Vallance-Owen Department of Medicine Prince of Wales Hospital, Chinese University of Hong Kong Shatin, NT Hong Kong Department of Chemical Pathology Prince of Wales Hospital, Chinese University of Hong Kong Shatin, NT Hong Kong Summary This study provides information on the prevalence of diabetes mellitus in a group of elderly Chinese subjects aged 60 and above living in the community in Hong Kong, and investigates the sensitivity of the urine sugar, random blood glucose, glycosylated haemoglobin, and fructosamine measurements compared to a glucose tolerance test in screening for diabetes mellitus in this population. Four hundred twenty-seven subjects aged 60 and above were studied. The National Diabetes Data Group Criteria were used for the diagnosis of diabetes. Those with a random blood glucose exceeding 12.5 mmol/l were considered diabetic, and all of these patients had glycosuria together with elevated total glycosylated haemoglobin and fractosamine concentrations. A diagnostic 75 g oral glucose tolerance test was performed on patients with one or more of the following abnormalities: glycosuria, random plasma blood glucose 7.8 mmol/l to 12.5 mmol/l, glycosylated haemoglobin 8.5%, and fructosamine 2.20 mmol/l. By these criteria, the prevalence of diabetes in this community was found to be 9.8%. An elevated random glucose greater than 11.1 mmol/l proved to be the only specific method of screening and glycosuria was found to be at least as good as fractosamine and HbA 1 . However, HbA 1 is more sensitive than random glucose, glycosuria or fructosamine in detecting impaired glucose tolerance. On the basis of this study, a higher reference range for glycosylated haemoglobin for the elderly alone is also suggested (5.74–9.34%).

Journal

Diabetologia – Springer Journals

Published: Nov 1, 1987

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