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Synthesis of fluorine-containing 3-hydroxyflavanones and isoflavones

Synthesis of fluorine-containing 3-hydroxyflavanones and isoflavones Fluorine-containing 3-hydroxyflavanones and isoflavones were synthesized by epoxidation of F-containing chalcones by hydrogen peroxide under basic conditions and subsequent intramolecular cyclization of the resulting epoxides using BF3·Et2O. The ratio of products depended on the presence and position of the F atom. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Chemistry of Natural Compounds Springer Journals

Synthesis of fluorine-containing 3-hydroxyflavanones and isoflavones

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References (14)

Publisher
Springer Journals
Copyright
Copyright © 2011 by Springer Science+Business Media, Inc.
Subject
Pharmacy; Pharmacy; Plant Sciences ; Organic Chemistry
ISSN
0009-3130
eISSN
1573-8388
DOI
10.1007/s10600-011-9824-5
Publisher site
See Article on Publisher Site

Abstract

Fluorine-containing 3-hydroxyflavanones and isoflavones were synthesized by epoxidation of F-containing chalcones by hydrogen peroxide under basic conditions and subsequent intramolecular cyclization of the resulting epoxides using BF3·Et2O. The ratio of products depended on the presence and position of the F atom.

Journal

Chemistry of Natural CompoundsSpringer Journals

Published: Apr 8, 2011

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