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Synthesis of 2-alkyl thio-substituted 4-oxo-3-p-tolyl-3,4,5,6-tetrahydrospiros-(Benzo[h]quinazoline-5,1′-cycloalkanes)

Synthesis of 2-alkyl thio-substituted... Reaction of 4-amino-3-carbethoxy-1,2-dihydrospiro(naphthalene-2,1′-cycloalkanes) with p-tolylisothio-cyanate gave 4-oxo-2-thioxo-3-p-tolyl-1,2,3,4,5,6-hexahydro(benzo[h]quinazoline-5,1′-cycloalkanes) which could be alkylated using various halo compounds to yield the corresponding S-alkyl derivatives. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Chemistry of Heterocyclic Compounds Springer Journals

Synthesis of 2-alkyl thio-substituted 4-oxo-3-p-tolyl-3,4,5,6-tetrahydrospiros-(Benzo[h]quinazoline-5,1′-cycloalkanes)

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Publisher
Springer Journals
Copyright
Copyright © 1999 by Kluwer Academic/Plenum Publishers
Subject
Chemistry; Organic Chemistry; Pharmacy
ISSN
0009-3122
eISSN
1573-8353
DOI
10.1007/BF02251821
Publisher site
See Article on Publisher Site

Abstract

Reaction of 4-amino-3-carbethoxy-1,2-dihydrospiro(naphthalene-2,1′-cycloalkanes) with p-tolylisothio-cyanate gave 4-oxo-2-thioxo-3-p-tolyl-1,2,3,4,5,6-hexahydro(benzo[h]quinazoline-5,1′-cycloalkanes) which could be alkylated using various halo compounds to yield the corresponding S-alkyl derivatives.

Journal

Chemistry of Heterocyclic CompoundsSpringer Journals

Published: Oct 25, 2005

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