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A. Hessel, T. Gunzelmann, M. Geyer, E. Brähler (2000)
Inanspruchnahme medizinischer Leistungen und Medikamenteneinnahme bei über 60jährigen in Deutschland –gesundheitliche, sozialstrukturelle, sozio-demographische und subjektive FaktorenZeitschrift für Gerontologie und Geriatrie, 33
J. Allard, R. Hébert, Maryse Rioux, Johannne Asselin, L. Voyer (2001)
Efficacy of a clinical medication review on the number of potentially inappropriate prescriptions prescribed for community-dwelling elderly people.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 164 9
M. Packer, P. Poole‐Wilson, P. Armstrong, J. Cleland, J. Horowitz, B. Massie, L. Rydén, K. Thygesen, B. Uretsky (1999)
Comparative effects of low and high doses of the angiotensin-converting enzyme inhibitor, lisinopril, on morbidity and mortality in chronic heart failure. ATLAS Study Group.Circulation, 100 23
A. Chobanian, G. Bakris, H. Black, W. Cushman, L. Green, J. Izzo, Daniel Jones, B. Materson, S. Oparil, J. Wright, E. Roccella (2003)
Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure.Hypertension, 42 6
E. Kvan, A. Reikvam (2004)
The problem of underdosing of angiotensin-converting enzyme inhibitors is markedly overrated: results from a study of patients discharged from hospital after an acute myocardial infarctionEuropean Journal of Clinical Pharmacology, 60
A. Al‐Windi, Dag Elmfeldt, Kurt Svärdsudd (2000)
The relationship between age, gender, well-being and symptoms, and the use of pharmaceuticals, herbal medicines and self-care products in a Swedish municipalityEuropean Journal of Clinical Pharmacology, 56
W. Remme, K. Swedberg (2001)
Guidelines for the diagnosis and treatment of chronic heart failure.European heart journal, 22 17
(2001)
Lipid-lowering treatment coronary artery disease: a pharmacoepidemiological survey in an outpatient clinic in Germany
Catherine Roe, Brenda Motheral, Fred Teitelbaum, Michael Rich (2000)
Compliance with and dosing of angiotensin-converting-enzyme inhibitors before and after hospitalization.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 57 2
B. Gage, M. Boechler, Amy Doggette, Gary Fortune, G. Flaker, M. Rich, M. Radford (2000)
Adverse outcomes and predictors of underuse of antithrombotic therapy in medicare beneficiaries with chronic atrial fibrillation.Stroke, 31 4
(1998)
Pre- scription of cardiovascular drugs in ambulatory care: a survey of ambulatory patients in a German University Hospital
(2001)
Effi- cacy of a clinical medication review on the number of poten- tially inappropriate prescriptions prescribed for community- dwelling elderly people
Aike Hessel, T. Gunzelmann, Michael Geyer, E. Brähler (2000)
[Utilization of medical services and medication intake of patients over 60 in Germany--health related, social structure related, socio-demographic and subjective factors].Zeitschrift fur Gerontologie und Geriatrie, 33 4
B. Briesacher, B. Stuart, Roseann Peluso (1999)
Drug use and prescribing problems in the community-dwelling elderly: a study of three state Medicaid programs.Clinical therapeutics, 21 12
M. Komajda, F. Follath, K. Swedberg, J. Cleland, J. Aguilar, A. Cohen-Solal, R. Dietz, A. Gavazzi, W. Gilst, R. Hobbs, J. Korewicki, H. Madeira, V. Moiseyev, I. Préda, J. Widimský, N. Freemantle, J. Eastaugh, J. Mason (2003)
The EuroHeart Failure Survey programme - a survey on the quality of care among patients with heart failure in Europe. Part 2: treatmentEuropean Heart Journal, 24
I. Nazareth, Ann Burton, Sally Shulman, Pauline Smith, A. Haines, Heather Timberall (2001)
A pharmacy discharge plan for hospitalized elderly patients--a randomized controlled trial.Age and ageing, 30 1
S. Harder, P. Thürmann, T. Huber, N. Rietbrock (2004)
Prescription of drugs not listed in a clinic's pharmacopoeia: supervision by clinical pharmacologistsEuropean Journal of Clinical Pharmacology, 40
B. Boeve, Joan Mccormick, Glenn Smith, T. Ferman, T. Rummans, T. Carpenter, R. Ivnik, E. Kokmen, E. Tangalos, S. Edland, D. Knopman, R. Petersen (2003)
Mild cognitive impairment in the oldest oldNeurology, 60
S. Meredith, P. Feldman, D. Frey, L. Giammarco, K. Hall, K. Arnold, N. Brown, W. Ray (2002)
Improving Medication Use in Newly Admitted Home Healthcare Patients: A Randomized Controlled TrialJournal of the American Geriatrics Society, 50
M. Beers (1997)
Explicit criteria for determining potentially inappropriate medication use by the elderly. An update.Archives of internal medicine, 157 14
T. Strandberg, K. Pitkala, S. Kulp, R. Tilvis (2001)
Use of cardiovascular drugs by home-dwelling coronary patients aged 75 years and olderEuropean Journal of Clinical Pharmacology, 57
J. Feely, P. McGettigan, A. Kelly (2000)
Growth in use of statins after trials is not targeted to most appropriate patientsClinical Pharmacology & Therapeutics, 67
(2001)
Task force for the diagnosis and treatment of chronic heart failure, European Society of Cardiology. Guidelines for the diagnosis and treatment of chronic heart failure
Panagiotis Papanikolaou, J. Ioannidis (2003)
Awareness of the side effects of possessed medications in a community settingEuropean Journal of Clinical Pharmacology, 58
S. Egger, J. Drewe, R. Schlienger (2003)
Potential drug–drug interactions in the medication of medical patients at hospital dischargeEuropean Journal of Clinical Pharmacology, 58
W. Himmel, B. Lönker, M. Kochen (1998)
Nonformulary drug requests at an academic hospital in Germany – the role of general practitioners' long-term medicationEuropean Journal of Clinical Pharmacology, 54
C. Gasse, C. Gasse, H. Hense, J. Stieber, Angela Döring, A. Liese, U. Keil (2001)
Assessing hypertension management in the community: trends of prevalence, detection, treatment, and control of hypertension in the MONICA Project, Augsburg 1984–1995Journal of Human Hypertension, 15
Wolfgang Himmel, M. Tabache, Michael Kochen (1996)
What happens to long-term medication when general practice patients are referred to hospital?European Journal of Clinical Pharmacology, 50
I. Holme, S. Tonstad (2004)
[Treatment with statins of the elderly].Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 124 2
(1999)
Comparative effects of low and high doses of the angiotensin-converting enzyme inhibitor, lisinopril, on mor- bidity and mortality in chronic heart failure
A. Siu, R. Kravitz, E. Keeler, K. Hemmerling, R. Kington, J. Davis, A. Mitchell, T. Burton, H. Morgenstern, M. Beers, D. Reuben (1996)
Postdischarge geriatric assessment of hospitalized frail elderly patients.Archives of internal medicine, 156 1
E. Hylek, A. Go, Yuchiao Chang, Nancy Jensvold, Lori Henault, J. Selby, D. Singer (2003)
Effect of intensity of oral anticoagulation on stroke severity and mortality in atrial fibrillation.The New England journal of medicine, 349 11
S. Meredith, P. Feldman, D. Frey, K. Hall, K. Arnold, N. Brown, W. Ray (2001)
Possible Medication Errors in Home Healthcare PatientsJournal of the American Geriatrics Society, 49
(2001)
MIR-1 und MITRA-1-Studiengruppen. Cur- rent prescription practice of CSE inhibitors at clinic discharge after acute myocardial infarct
K. Dijk, C. Vries, P. Berg, Jacobus Brouwers, de Berg (2000)
Drug utilisation in Dutch nursing homesEuropean Journal of Clinical Pharmacology, 55
(1998)
scription of cardiovascular drugs in ambulatory care : a survey of ambulatory patients in a German University Hospital
(2002)
Prevalence of atrial fibrillation and antithrombotic pro- phylaxis in emergency department patients
H. Krumholz, M. Radford, Yun Wang, Jersey Chen, A. Heiat, T. Marciniak (1998)
National use and effectiveness of beta-blockers for the treatment of elderly patients after acute myocardial infarction: National Cooperative Cardiovascular Project.JAMA, 280 7
Wolfgang Himmel, Michael Kochen, U. Sorns, E. Hummers-Pradier (2004)
Drug changes at the interface between primary and secondary care.International journal of clinical pharmacology and therapeutics, 42 2
J. Okuno, H. Yanagi, S. Tomura, M. Oka, S. Hara, C. Hirano, S. Tsuchiya (1999)
Compliance and medication knowledge among elderly Japanese home-care recipientsEuropean Journal of Clinical Pharmacology, 55
W. Remme, K. Swedberg (2002)
Comprehensive guidelines for the diagnosis and treatment of chronic heart failure Task force for the diagnosis and treatment of chronic heart failure of the European Society of CardiologyEuropean Journal of Heart Failure, 4
D. Pittrow, W. Kirch, P. Bramlage, Hendrik Lehnert, M. Höfler, T. Unger, Arya Sharma, H. Wittchen (2004)
Patterns of antihypertensive drug utilization in primary careEuropean Journal of Clinical Pharmacology, 60
S. Lewis (2004)
Statin therapy in the elderly: observational and randomized controlled trials support event reduction.The American journal of geriatric cardiology, 13 3 Suppl 1
P. Scott, A. Pancioli, L. Davis, S. Frederiksen, John Eckman (2002)
Prevalence of Atrial Fibrillation and Antithrombotic Prophylaxis in Emergency Department PatientsStroke: Journal of the American Heart Association, 33
P. Rochon, J. Tu, G. Anderson, J. Gurwitz, J. Clark, P. Lau, J. Szalai, K. Sykora, C. Naylor (2000)
Rate of heart failure and 1-year survival for older people receiving low-dose β-blocker therapy after myocardial infarctionThe Lancet, 356
A. Chobanian, G. Bakris, H. Black, W. Cushman, L. Green, J. Izzo, Daniel Jones, B. Materson, S. Oparil, J. Wright, E. Roccella (2003)
The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report.JAMA, 289 19
S. Harder, P. Thürmann, C. Thierolf, H. Klepzig (1998)
Prescription of cardiovascular drugs in outpatient care: a survey of outpatients in a German university hospital.International journal of clinical pharmacology and therapeutics, 36 4
A. Stuck, M. Beers, A. Steiner, H. Aronow, L. Rubenstein, J. Beck (1994)
Inappropriate medication use in community-residing older persons.Archives of internal medicine, 154 19
K. Swedberg, J. Cleland, H. Dargie, H. Drexler, F. Follath, M. Komajda, L. Tavazzi, O. Smiseth, A. Gavazzi, A. Haverich, A. Hoes, T. Jaarsma, J. Korewicki, Samuel Lévy, C. Linde, J. López-Sendón, M. Nieminen, L. Pierard, W. Remme (2005)
Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005): The Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology.European heart journal, 26 11
H. Kerek-Bodden, H. Koch, G. Brenner, G. Flatten (2000)
[Diagnostic spectrum and treatment requirements of general practice clients. Results of the ADT Panel of the Central Institute of National Health Insurance Management].Zeitschrift fur arztliche Fortbildung und Qualitatssicherung, 94 1
Yating Chen, Yung Wang, M. Radford, H. Krumholz (2001)
Angiotensin-converting enzyme inhibitor dosages in elderly patients with heart failure.American heart journal, 141 3
A. Golden, R. Preston, S. Barnett, M. Llorente, K. Hamdan, M. Silverman (1999)
Inappropriate Medication Prescribing in Homebound Older AdultsJournal of the American Geriatrics Society, 47
(2000)
Inanspruchnahme medizinischer Leistungen und Medikamenteneinnahme bei Áber 60jÂhrigen in Deutschland
J Coste, A Venot (1999)
An epidemiologic approach to drug prescribing quality assessmentMed Care, 37
P. Blenkiron (1996)
The elderly and their medication: understanding and compliance in a family practice.Postgraduate Medical Journal, 72
TE Strandberg, K Pitkala, S Kulp, RS Tilvis (2001)
Use of cardiovascular drugs by home-dwelling coronary patients aged 75 years and older (a population-based cross-sectional survey in Helsinki, Finland)Eur J Clin Pharmacol, 57
Orinda Schneitman-McIntire, Tracy Farnen, Nancy Gordon, Jim Chan, William Toy (1996)
Medication misadventures resulting in emergency department visits at and HMO medical center.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 53 12
S. Harder, O. Mohr, H. Klepzig (2001)
Lipid-lowering treatment in coronary artery disease: a survey in an ambulatory outpatient clinic.International journal of clinical pharmacology and therapeutics, 39 12
Joël Coste, Alain Venot (1999)
An epidemiologic approach to drug prescribing quality assessment: a study in primary care practice in France.Medical care, 37 12
AV Chobanian (2003)
National Heart, Lung, and Blood Institute; National High Blood Pressure Education Program Coordinating Committee. In: 7th report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressureHypertension, 42
T. Bungard, M. Ackman, Geotham Ho, R. Tsuyuki (2000)
Adequacy of Anticoagulation in Patients with Atrial Fibrillation Coming to a HospitalPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 20
In a group of elderly patients over 65 years of age with at least two cardiovascular diagnoses requiring chronic medication (n=424), drug therapy at hospital discharge and at home thereafter was followed for a 1-year period. Two home visits took place at 3 months and 12 months after initial discharge. A median of six prescriptions had already been given at the time of discharge; this number increased slightly during ambulatory follow-up. After 1 year, about 30% of the patients had to take more than ten dosing units per day. After discharge, about 50% of all prescriptions were subject to changes in the choice of the preparation (brand-generic) or the agent used [within a class of similar agents, e.g. angiotensin converting enzyme inhibitors (ACIs)]. The prescription of some problematic agents (benzodiazepines, non-steroidal anti-inflammatory agents) increased during the ambulatory follow-up, but pivotal medications for cardiovascular indications (e.g., ACI) given at discharge were maintained. Over-the-counter (OTC) drugs—which were not part of the discharge medication—contributed to 12% of all drugs taken at V4. The majority of the prescriptions (95% of about 2,000 prescriptions surveyed at each visit) was in agreement with the drug’s approval status and was appropriate in terms of absence of contraindications. At home visits, therapy with ACI or beta-blocking agents was in agreement with clinical guidelines, although under-dosing was obvious. Blood pressure control (<140/90 mmHg) was achieved in 61% of the patients at discharge and deteriorated to 45% after 1 year; international normalized ratio control in patients with oral anticoagulation also declined (control rate 57% at discharge, 46% after 1 year). Statins as secondary prevention were given at discharge in only 60% of suitable patients, declining to about 50% in ambulatory visits. Diabetic control was not present in 35% of the patients at discharge or at home. Properties of or reason for their medication could be given for the majority (70–80%) of the prescriptions; these quotations were, however, cursory and almost nothing was known about medication risks. At home visits, non-compliance was admitted for approximately 8% of the prescriptions. In conclusion, for pivotal indications, family doctors widely followed the discharge recommendations, but deficits in ambulatory prescriptions and poor performance of the medication were in part already employed at the time of discharge from the hospital. The lack of a patient’s knowledge about their own medication is precarious.
European Journal of Clinical Pharmacology – Springer Journals
Published: Dec 1, 2004
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