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H. Molewijk, A. Poel, J. Mos, J. Heyden, B. Olivier, B. Olivier (2005)
Conditioned ultrasonic distress vocalizations in adult male rats as a behavioural paradigm for screening anti-panic drugsPsychopharmacology, 117
J. Vry (1995)
5-HT1A receptor agonists: recent developments and controversial issues.Psychopharmacology, 121 1
J. Vry, U. Benz, R. Schreiber, J. Traber (1993)
Shock-induced ultrasonic vocalization in young adult rats: a model for testing putative anti-anxiety drugs.European journal of pharmacology, 249 3
H. Sommermeyer, R. Schreiber, J. Greuel, J. Vry, T. Glaser (1993)
Anxiolytic effects of the 5-HT1A receptor agonist ipsapirone in the rat: neurobiological correlates.European journal of pharmacology, 240 1
(1994)
A pharmacological profile of WAY-100635, a potent and selective 5-HT1A receptor antagonist
T. Jolas, R. Schreiber, A. Laporte, M. Chastanet, J. Vry, T. Glaser, J. Adrien, M. Hamon (1995)
Are postsynaptic 5-HT1A receptors involved in the anxiolytic effects of 5-HT1A receptor agonists and in their inhibitory effects on the firing of serotonergic neurons in the rat?The Journal of pharmacology and experimental therapeutics, 272 2
R. Schreiber, J. Vry (1993)
Neuronal circuits involved in the anxiolytic effects of the 5-HT1A receptor agonists 8-OH-DPAT ipsapirone and buspirone in the rat.European journal of pharmacology, 249 3
213 125 125 1 1 S. Maurel Remy R. Schreiber M. Dalmus J. De Vry Institute for Neurobiology, Troponwerke GmbH & Co. KG Berliner Strasse 156 D-51063 Köln Germany Abstract In the rat shock-induced ultrasonic vocalization test, the anxiolytic effects of the 5-HT 1A receptor agonist 8-hydroxy-2-(di- n -propylamino)tetralin (8-OH-DPAT) obtained after systemic (IP) and intracerebral injection into the dorsal raphe nucleus (DRN) were selectively abolished by pretreatment with the 5-HT 1A receptor antagonist WAY-100635 ( N -(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)- N -(2-pyridinyl) cyclo-hexanecarboxamide trihydrochloride). This blockade was demonstrated both after systemic and DRN application of WAY-100635. Therefore, it is concluded that the anxiolytic effects of 8-OH-DPAT are mediated by activation of somatodendritic 5-HT 1A receptors.
Psychopharmacology – Springer Journals
Published: May 1, 1996
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