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Smouldering systemic mastocytosis with lymph node involvement mimicking malignant lymphoma

Smouldering systemic mastocytosis with lymph node involvement mimicking malignant lymphoma Ann Hematol (2014) 93:1603–1604 DOI 10.1007/s00277-013-1993-9 LETTER TO THE EDITOR Smouldering systemic mastocytosis with lymph node involvement mimicking malignant lymphoma Z. Xu & B. Jamison & I. Bence-Bruckler Received: 15 November 2013 /Accepted: 5 December 2013 /Published online: 15 December 2013 Springer-Verlag Berlin Heidelberg 2013 Dear Editor, abnormal cells possessed a paratrabecular pattern, cuffing A 65-year-old male was referred for assessment of enlarged the bone trabecular (Fig. 1c). The abnormal cells accounted abdominal lymphadenopathy (Fig. 1a) detected by a CT/ for 30-40 % of bone marrow mononuclear cells, morpholog- abdomen 3 years ago. CT scan also demonstrated that the ically suggestive of mast cells. The abnormal cells were vertebral bodies and pelvic bones had diffusely heterogeneous positive for tryptase, CD25 (Fig. 1d, e), CD117, and CD68, appearance which might relate to sclerotic disease (Fig. 1b). A confirming that they were neoplastic mast cells. CD3 and repeated CT/abdomen confirmed a progressive lymphadenop- CD20 showed no lymphoma involvement in the bone mar- athy in the retroperitoneal and mesenteric region with spleno- row. According to WHO systemic mastocytosis (SM) diag- megaly and sclerotic bone lesions. Patient had no constitu- nostic criteria, it met the major criteria and two minor criteria. tional symptoms. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Hematology Springer Journals

Smouldering systemic mastocytosis with lymph node involvement mimicking malignant lymphoma

Annals of Hematology , Volume 93 (9) – Sep 1, 2014

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References (4)

Publisher
Springer Journals
Copyright
Copyright © 2014 by Springer-Verlag Berlin Heidelberg
Subject
Medicine & Public Health; Hematology; Oncology
ISSN
0939-5555
eISSN
1432-0584
DOI
10.1007/s00277-013-1993-9
pmid
24337517
Publisher site
See Article on Publisher Site

Abstract

Ann Hematol (2014) 93:1603–1604 DOI 10.1007/s00277-013-1993-9 LETTER TO THE EDITOR Smouldering systemic mastocytosis with lymph node involvement mimicking malignant lymphoma Z. Xu & B. Jamison & I. Bence-Bruckler Received: 15 November 2013 /Accepted: 5 December 2013 /Published online: 15 December 2013 Springer-Verlag Berlin Heidelberg 2013 Dear Editor, abnormal cells possessed a paratrabecular pattern, cuffing A 65-year-old male was referred for assessment of enlarged the bone trabecular (Fig. 1c). The abnormal cells accounted abdominal lymphadenopathy (Fig. 1a) detected by a CT/ for 30-40 % of bone marrow mononuclear cells, morpholog- abdomen 3 years ago. CT scan also demonstrated that the ically suggestive of mast cells. The abnormal cells were vertebral bodies and pelvic bones had diffusely heterogeneous positive for tryptase, CD25 (Fig. 1d, e), CD117, and CD68, appearance which might relate to sclerotic disease (Fig. 1b). A confirming that they were neoplastic mast cells. CD3 and repeated CT/abdomen confirmed a progressive lymphadenop- CD20 showed no lymphoma involvement in the bone mar- athy in the retroperitoneal and mesenteric region with spleno- row. According to WHO systemic mastocytosis (SM) diag- megaly and sclerotic bone lesions. Patient had no constitu- nostic criteria, it met the major criteria and two minor criteria. tional symptoms.

Journal

Annals of HematologySpringer Journals

Published: Sep 1, 2014

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