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Pharmaceutical Chemistry Journal Vol. 35, No. 2, 2001 MEDICINAL PLANTS SELECTING THE OPTIMUM COMPOSITION AND DEVELOPING THE TECHNOLOGY FOR TABLETS OF MILK-WHITE IRIS EXTRACT 1 1 1 1 S. A. Minina, T. V. Astakhova, N. I. Pryakhina, and G. Abu-Skhela Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 35, No. 2, pp. 24 – 26, February, 2001. Original article submitted November 23, 1998. Species of milk-white iris (Iris lactea Pall.) occur widely layer. The coat weight accounts for 7.41% of the total tablet in Transbaikalia. These herbs are characterized by a high weight. The moisture penetration rate at 100% humidity cal- content of polyphenolic compounds, including flavones, culated for a 50-m-thick MC coating was 0.32 mg(cm h) xanthones, and phenolcarboxylic acids [1]. Based on the re- and the equilibrium moisture content (over 168 h) was sults of pharmacological investigations, it was established 14 mgcm . The hydrophobic oily substrate markedly re- that the dry extract of milk-white iris herbs is nontoxic and duced the water penetration. produces immunostimulant, antiinflammatory, and The tabletization regime was optimized by the method of antihypoxant effects [2, 3]. Taking into account the recom- mathematical experiment planing according to Box – Wil- mendations of pharmacists and the
Pharmaceutical Chemistry Journal – Springer Journals
Published: Oct 9, 2004
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