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References (8)
-
L. Mohamed, M. Taourirte, A. Rochdi, H. Lazrek, J. Vasseur, J. Engels, C. Pannecouque, E. Clercq (2003)
Synthesis of New Homo and Heterodimers of 2′,3′-Dideoxyinosine (ddi) Using Ester LinkagesNucleosides, Nucleotides & Nucleic Acids, 22
-
M. Sheha, A. Khedr, Hosny Elsherief (2002)
Biological and metabolic study of naproxen-propyphenazone mutual prodrug.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 17 3
-
J. Leppänen, J. Huuskonen, T. Nevalainen, J. Gynther, H. Taipale, T. Järvinen (2002)
Design and synthesis of a novel L-dopa-entacapone codrug.Journal of medicinal chemistry, 45 6
-
K. Yoshimoto, Y. Itatani, Y. Tsuda (1980)
^ C-Nuclear Magnetic Resonance (NMR) Spectra of O-Acylglucoses. Additivity of Shift Parameters and Its Application to Structure ElucidationsChemical & Pharmaceutical Bulletin, 28
-
F. Menger, Michael Rourk (1997)
Synthesis and Reactivity of 5-Fluorouracil/Cytarabine Mutual ProdrugsJournal of Organic Chemistry, 62
-
H. Bundgaard (1985)
Design of prodrugs -
and Nudelman, A. Rephaeli (2000)
Novel mutual prodrug of retinoic and butyric acids with enhanced anticancer activity.Journal of medicinal chemistry, 43 15
-
R. Silverman (1992)
The Organic Chemistry of Drug Design and Drug Action
- Publisher
- Springer Journals
- Copyright
- Copyright © 2005 by Springer
- Subject
- Chemistry; Biotechnology; Applied Microbiology; Biochemistry, general; Microbiology
- ISSN
- 0141-5492
- eISSN
- 1573-6776
- DOI
- 10.1007/s10529-004-7335-1
- pmid
- 15703874
- Publisher site
- See Article on Publisher Site
Abstract
Novel mutual pro-drugs in which 2′,3′-dideoxyinosine anti-HIV (human immunodeficiency virus) drug and 3-octadecyloxy-propane-1,2-diol anti-inflammatory drug were attached to the same molecule via different biodegradable linkages, were synthesized through two-step enzymatic transesterification by a commercial lipase in acetone.
Journal
Biotechnology Letters – Springer Journals
Published: Dec 8, 2004