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Ann Hematol (2014) 93:1801–1803 DOI 10.1007/s00277-014-2018-z LETTER TO THE EDITOR Independent growth of diffuse large B cell lymphoma and angioimmunoblastic T cell lymphoma originating from composite lymphoma Rie Tabata & Chiharu Tabata & Ryoji Yasumizu & Masaru Kojima Received: 14 December 2013 /Accepted: 12 January 2014 /Published online: 1 February 2014 Springer-Verlag Berlin Heidelberg 2014 Dear Editor, The architecture of the original inguinal LN was A 75-year-old woman was admitted to a hospital because of completely effaced. High endothelial venules-like ves- multiple surface lymph node (LN) swelling, fever, appetite sels (HEV) were increased. Medium- to large-sized lym- loss, peripheral edema, and dyspnea. F-fluorodeoxyglucose phoid cells with a clear cytoplasm proliferated and positron emission tomography revealed the involvement of associated with the prominent meshwork of follicular multiple LNs and spleen. Laboratory findings were almost dendritic cells (FDC, Fig. 1a–c). The results of an normal except for LDH (631 IU/l), C-reactive protein immunohistochemical study demonstrated that tumor (7.3 mg/dl), and soluble IL-2 receptor (3,096 U/ml). Serum cells were positive for programmed death-1 (PD-1), levels of IgG, IgA, and IgM were normal without M protein or CD4, andCD10(Fig. 1d–f), but negative for CD3. Bence-Jones protein. Right inguinal LN biopsy was performed Some
Annals of Hematology – Springer Journals
Published: Oct 1, 2014
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