Incorporation of 3 H 2 O into lipids of adult male rat lung after castration

Gómez N.; Ojeda M.; Gimenez M.

doi:10.1007/BF02349394

$The aim of this study was to determine whether testosterone regulates the rate of lipid synthesis in lung. Rats were either sham-operated controls (Co) or castrated (Ca)·( 3 H) H 2 O was administered in vivo, twenty-one days after castration. The animals were sacrificed 1h later to ensure that the newly synthesized lipids in the lung had been labeled. The radioactivity incorporated in the different lipid fractions that had been separated by TLC was counted. The results are expressed in ng 3 H incorporated/h/mg lipids. We observed that the incorporation of 3 H in total lipids, phospholipids and free cholesterol increased, while trygliceride and esterified cholesterol did not change in castrated rats in relation to the control. These results suggest that the rate of lipid synthesis in the lung is regulated, directly or indirectly by androgens.$

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Incorporation of 3 H 2 O into lipids of adult male rat lung after castration

N., Gómez; M., Ojeda; M., Gimenez

Follow Journal of Radioanalytical and Nuclear Chemistry , Volume 240 (2) Springer Journals – May 1, 1999

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Incorporation of 3 H 2 O into lipids of adult male rat lung after castration

N., Gómez; M., Ojeda; M., Gimenez

Follow Journal of Radioanalytical and Nuclear Chemistry , Volume 240 (2) Springer Journals – May 1, 1999

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