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R. Beninger, B. Hahn (1983)
Pimozide blocks establishment but not expression of amphetamine-produced environment-specific conditioning.Science, 220 4603
R. Herz, R. Beninger (2004)
Comparison of the ability of (+)-amphetamine and caffeine to produce environment-specific conditioningPsychopharmacology, 92
R. Pickens, W. Crowder (2004)
Effects of CS-US interval on conditioning of drug response, with assessment of speed of conditioningPsychopharmacologia, 11
T. Robinson, J. Becker (1986)
Enduring changes in brain and behavior produced by chronic amphetamine administration: A review and evaluation of animal models of amphetamine psychosisBrain Research Reviews, 11
R. Beninger (1983)
The role of dopamine in locomotor activity and learningBrain Research Reviews, 6
(1984)
Conditioning, sensitization, and kindling: Implications for the course of affective illness
M. Poncelet, L. Dangoumau, P. Soubrié, P. Simon (2004)
Effects of neuroleptic drugs, clonidine and lithium on the expression of conditioned behavioral excitation in ratsPsychopharmacology, 92
E. Mazurski, R. Beninger (1987)
Environment-specific conditioning and sensitization with (+)-amphetaminePharmacology Biochemistry and Behavior, 27
R. Beninger, R. Herz (1986)
Pimozide blocks establishment but not expression of cocaine-produced environment-specific conditioning.Life sciences, 38 15
S. Schiff (1982)
Conditioned dopaminergic activity.Biological psychiatry, 17 2
David Clark, F. White (1987)
Review: D1 dopamine receptor—the search for a function: A critical evaluation of the D1/D2 dopamine receptor classification and its functional implicationsSynapse, 1
Robert Miller, J. Wickens, R. Beninger (1990)
Dopamine D-1 and D-2 receptors in relation to reward and performance: A case for the D-1 receptor as a primary site of therapeutic action of neuroleptic drugsProgress in Neurobiology, 34
Gordon Barr, N. Sharpless, Stanley Cooper, Stanley Schiff, William Paredes, Wagner Bridger (1983)
Classical conditioning, decay and extinction of cocaine-induced hyperactivity and stereotypy.Life sciences, 33 14
(1975)
The action of central nervous system stimulating drugs: A general theory concerning amphetamine effects
R. Beninger, D. Hoffman, E. Mazurski (1989)
Receptor subtype-specific dopaminergic agents and conditioned behaviorNeuroscience & Biobehavioral Reviews, 13
C. Graaf, J. Korf (2004)
Conditional tolerance to haloperidol-induced catalepsy is not caused by striatal dopamine receptor supersensitivityPsychopharmacology, 90
H. Möller, K. Nowak, K. Kuschinsky (2004)
Conditioning of pre- and post-synaptic behavioural responses to the dopamine receptor agonist apomorphine in ratsPsychopharmacology, 91
J. Stoof, P. Verheijden (1986)
D-2 receptor stimulation inhibits cyclic AMP formation brought about by D-1 receptor stimulation in rat neostriatum but not nucleus accumbens.European journal of pharmacology, 129 1-2
H. Tilson, R. Rech (1973)
Conditioned drug effects and absence of tolerance to d-amphetamine induced motor activity ☆Pharmacology, Biochemistry and Behavior, 1
E. Mazurski, R. Beninger (1988)
The dopamine D-2 agonist quinpirole produces environment-specific conditioned activityPharmacology Biochemistry and Behavior, 30
J. Kebabian, D. Calne (1979)
Multiple receptors for dopamineNature, 277
J. Morgan (2005)
Design and Analysis: A Researcher's HandbookTechnometrics, 47
C. Poulos, R. Hinson (1982)
Pavlovian conditional tolerance to haloperidol catalepsy: evidence of dynamic adaptation in the dopaminergic system.Science, 218 4571
D. Aaker, G. Keppel (1976)
Design and Analysis: A Researcher's HandbookJournal of Marketing Research, 13
R. Beninger, T. Cooper, E. Mazurski (1985)
Automating the measurement of locomotor activity.Neurobehavioral toxicology and teratology, 7 1
213 105 105 1 1 Evalynn J. Mazurski Richard J. Beninger Department of Psychology Queen's University K7L 3N6 Kingston Ontario Canada Abstract Classically conditioned locomotor activity has been demonstrated by pairing injections of dopamine agonists or antagonists with specific environmental stimuli. The present studies investigated conditioning using drugs with varying selectivity for the dopamine D1 or D2 receptor. Experiment 1 assessed conditioning in groups of rats using the indirect acting agonist (+)-amphetamine (2.0 mg/kg), and the D1 agonist SKF 38393 (10.0 mg/kg), the D2 agonist quinpirole (2.5 mg/kg), the D1 and D2 antagonists, SCH 23390 (0.05 mg/kg) and metoclopramide (25.0 mg/kg), respectively. Paired groups received nine 2-h drug-environment (automated activity monitoring chambers) pairings whereas Unpaired groups received the stimuli explicitly unpaired. Test revealed conditioned hyperactivity with each agonist and metoclopramide whereas conditioned hypoactivity was seen with SCH 23390. Experiment 2 assessed the interaction of these agonists and antagonists on the establishment of conditioned activity. Paired groups received an agonist and antagonist during conditioning sessions. SCH 23390 blocked conditioning based on (+)-amphetamine and SKF 38393 but not quinpirole. Metoclopramide (10.0 mg/kg) blocked conditioning based on quinpirole but not SKF 38393. Metoclopramide (25.0 mg/kg) also did not block (+)-amphetamine-induced conditioning. These studies suggested that drug-induced alterations at either D1 or D2 receptors may be involved in conditioned locomotion.
Psychopharmacology – Springer Journals
Published: Mar 1, 1991
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