Access the full text.
Sign up today, get DeepDyve free for 14 days.
M. Okubo, J. Izumi, T. Hosotani, T. Yamashita (1997)
Production of micron-sized monodispersed core/shell polymethyl methacrylate/polystyrene particles by seeded dispersion polymerizationColloid and Polymer Science, 275
Hidenobu Shimizu, K. Fujimoto, H. Kawaguchi (1999)
Refolding of protein using thiol-carrying latex particlesColloids and Surfaces A: Physicochemical and Engineering Aspects, 153
M. Okubo, H. Ahmad, Toyoko Suzuki (1998)
Synthesis of temperature-sensitive micron-sized monodispersed composite polymer particles and its application as a carrier for biomoleculesColloid and Polymer Science, 276
H. Ahmad, M. Okubo, Y. Kamatari, H. Minami (2002)
Structural conformation of biomolecules released from temperature-sensitive composite polymer particles – a study by circular dichroismColloid and Polymer Science, 280
H. Ahmad, M. Rahman, M. Miah, A. Ali (2001)
A study on the production of PMMA/P(MMA-AAm) composite polymer particles and the effect of acrylamide content on the adsorption behaviors of biomoleculesColloid and Polymer Science, 279
F. Candau, R. Ottewill (1990)
An Introduction to Polymer Colloids
K. Fujimoto, Y. Mizuhara, Nobuko Tamura, H. Kawaguchi (1993)
Interactions between Thermosensitive Hydrogel Microspheres and ProteinsJournal of Intelligent Material Systems and Structures, 4
Modification of surface properties of polymer particles suitable for biomedical application has been done by incorporating acrylic acid (AA) as a hydrophilic component. First, submicron-sized poly(methyl methacrylate) seed particles were prepared by soap-free emulsion polymerization. Then, seeded emulsion copolymerizations were carried out with varying proportions of AA and methyl methacrylate (MMA). MMA was used as a comonomer to prevent the dissolution of AA from the polymer particles. The adsorption behaviors of different biomolecules indicate that the surface of the composite polymer particles is sufficiently hydrophilic, particularly at higher AA content. Specific activities of adsorbed trypsin on the composite polymer particles were also comparatively high compared to free trypsin, which suggests that the adsorbed trypsin undergoes only slight conformational change owing to the interaction with the surface of particles.
Colloid Polymer Science – Springer Journals
Published: Mar 4, 2003
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.