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B. Gibbs, D. Shapton (1968)
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H. Rapoport, N. Castagnoli (1962)
2,2″-BipyrroleJournal of the American Chemical Society, 84
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227 27 27 4 4 R. J. Andersen M. S. Wolfe D. J. Faulkner Scripps Institution of Oceanography University of California San Diego, La Jolla California USA Abstract An antibiotic-producing Chromobacter was isolated from a sea-water sample from the North Pacific Gyre. The bacterium produces 3 bromine-containing metabolites: tetrabromopyrrole, 2-(2′-hydroxy-3′, 5′-dibromophenyl)-3, 4, 5-tribromopyrrole, and hexabromo-2, 2′-bipyrrole. It also synthesizes n-propyl 4-hydroxybenzoate and 4-hydroxybenzaldehyde. Some of these compounds were shown to be responsible for autoinhibition of the Chromobacterium itself, as well as for antibiotic action against other kinds of bacteria.
Marine Biology – Springer Journals
Published: Dec 1, 1974
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