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Autotoxic antibiotic production by a marine Chromobacterium

Autotoxic antibiotic production by a marine Chromobacterium 227 27 27 4 4 R. J. Andersen M. S. Wolfe D. J. Faulkner Scripps Institution of Oceanography University of California San Diego, La Jolla California USA Abstract An antibiotic-producing Chromobacter was isolated from a sea-water sample from the North Pacific Gyre. The bacterium produces 3 bromine-containing metabolites: tetrabromopyrrole, 2-(2′-hydroxy-3′, 5′-dibromophenyl)-3, 4, 5-tribromopyrrole, and hexabromo-2, 2′-bipyrrole. It also synthesizes n-propyl 4-hydroxybenzoate and 4-hydroxybenzaldehyde. Some of these compounds were shown to be responsible for autoinhibition of the Chromobacterium itself, as well as for antibiotic action against other kinds of bacteria. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Marine Biology Springer Journals

Autotoxic antibiotic production by a marine Chromobacterium

Marine Biology , Volume 27 (4) – Dec 1, 1974

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References (10)

Publisher
Springer Journals
Copyright
Copyright © 1974 by Springer-Verlag
Subject
Life Sciences; Biomedicine general; Oceanography; Ecology; Microbiology; Zoology
ISSN
0025-3162
eISSN
1432-1793
DOI
10.1007/BF00394363
Publisher site
See Article on Publisher Site

Abstract

227 27 27 4 4 R. J. Andersen M. S. Wolfe D. J. Faulkner Scripps Institution of Oceanography University of California San Diego, La Jolla California USA Abstract An antibiotic-producing Chromobacter was isolated from a sea-water sample from the North Pacific Gyre. The bacterium produces 3 bromine-containing metabolites: tetrabromopyrrole, 2-(2′-hydroxy-3′, 5′-dibromophenyl)-3, 4, 5-tribromopyrrole, and hexabromo-2, 2′-bipyrrole. It also synthesizes n-propyl 4-hydroxybenzoate and 4-hydroxybenzaldehyde. Some of these compounds were shown to be responsible for autoinhibition of the Chromobacterium itself, as well as for antibiotic action against other kinds of bacteria.

Journal

Marine BiologySpringer Journals

Published: Dec 1, 1974

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