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Acquired haemophilia in a patient with discoid lupus

Acquired haemophilia in a patient with discoid lupus Ann Hematol (2011) 90:119–120 DOI 10.1007/s00277-010-0972-7 LETTER TO THE EDITOR Iris Appelmann & Christoph Biermann & Inken Hartig & Wolfgang E. Berdel & Rolf Mesters Received: 14 December 2009 /Accepted: 19 April 2010 /Published online: 14 May 2010 Springer-Verlag 2010 Dear Editor, ment syndrome) was diagnosed by clinical examination and Acquired haemophilia A is a rare but potentially life- ultrasound. Neither the patient’s history nor his family threatening bleeding disorder caused by autoantibodies history gave evidence for bleeding disorders. Laboratory against the coagulation factor (F) VIII (FVIII inhibitor) findings revealed an isolated prolonged activated partial which is in some cases associated with autoimmune thromboplastin time (aPTT) with a normal prothrombin diseases, solid tumours, haemotologic malignancies or can time (PT), a normal platelet count and a reduced haemo- occur in the post-partum period. For further information globin level. After repeated unsuccessful surgical treatment concerning the pathophysiology of acquired haemophilia, and recurrence of the severe tissue haematoma, the patient please refer to [1]. was referred to the University Hospital of Muenster. The Mortality is rather high in newly diagnosed acquired coagulation work-up revealed a tremendously reduced level haemophilia ranging from 8% to 22% in different studies of FVIII activity (<1%), which http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Hematology Springer Journals

Acquired haemophilia in a patient with discoid lupus

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References (13)

Publisher
Springer Journals
Copyright
Copyright © 2011 by Springer-Verlag
Subject
Medicine & Public Health; Oncology; Hematology
ISSN
0939-5555
eISSN
1432-0584
DOI
10.1007/s00277-010-0972-7
pmid
20467746
Publisher site
See Article on Publisher Site

Abstract

Ann Hematol (2011) 90:119–120 DOI 10.1007/s00277-010-0972-7 LETTER TO THE EDITOR Iris Appelmann & Christoph Biermann & Inken Hartig & Wolfgang E. Berdel & Rolf Mesters Received: 14 December 2009 /Accepted: 19 April 2010 /Published online: 14 May 2010 Springer-Verlag 2010 Dear Editor, ment syndrome) was diagnosed by clinical examination and Acquired haemophilia A is a rare but potentially life- ultrasound. Neither the patient’s history nor his family threatening bleeding disorder caused by autoantibodies history gave evidence for bleeding disorders. Laboratory against the coagulation factor (F) VIII (FVIII inhibitor) findings revealed an isolated prolonged activated partial which is in some cases associated with autoimmune thromboplastin time (aPTT) with a normal prothrombin diseases, solid tumours, haemotologic malignancies or can time (PT), a normal platelet count and a reduced haemo- occur in the post-partum period. For further information globin level. After repeated unsuccessful surgical treatment concerning the pathophysiology of acquired haemophilia, and recurrence of the severe tissue haematoma, the patient please refer to [1]. was referred to the University Hospital of Muenster. The Mortality is rather high in newly diagnosed acquired coagulation work-up revealed a tremendously reduced level haemophilia ranging from 8% to 22% in different studies of FVIII activity (<1%), which

Journal

Annals of Hematology – Springer Journals

Published: Jan 1, 2011

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