S15 Pl 01 Experimental Evolution: Generatg Biological Novelty for Functional and Genetic Analyses AF Bennett Department of Ecology and Evolutionary Biology, University of California, Irve It is now possible to genetically engeer organisms as subjects for physiological studies. Transgenics is a now familiar method for such transformations, but an alternative and complementary technique for generatg biological novelty is experimental evolution. The latter has several advantages, cludg modification of multiple characters one experiment, the production of advantageous traits, the testg of hypotheses concerng the evolution of physiological traits, and the identification of previously unsuspected factors volved adaptation. Evolutionary experiments will be discussed that resulted the successful production of new variants with enhanced function their new environments. Each experiment successfully tested hypotheses concerng physiological evolution, and each case, unanticipated results emerged, suggestg previously unsuspected adaptive pathways and mechanisms. addition, replicate populations each experiment adjusted to their common environment by several different means, dicatg that physiological evolution may follow diverse stochastic pathways durg adaptation. (Supported by NSF Grant IBN9905980 and NASA Grant 632731 .) Pl 03 Mechanisms of Surfactant Exocytosis from Type II Pneumocytes P Dietl, T Haller, M Frick, N Mair, W Sger, M Ritsch-Marte, H Sammer, K Maly, C
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Abstracts (ABSTRACTS DPG)
Follow Pflügers Archiv European Journal of Physiologyl of Physiology
, Volume 445 (1)
Springer Journals – Feb 1, 2003
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