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213 28 28 3 3 R. B. Williams L. K. Y. Ng F. Lamprecht K. Roth I. J. Kopin Laboratory of Clinical Science and Laboratory of Clinical Psychobiology National Institute of Mental Health Bethesda Maryland Abstract The effects of δ 9 -tetrahydrocannabinol upon rat blood pressure were studied in control rats and in rats subjected to repeated immobilization stress over seven days. The immobilization stress was associated with a significant blood pressure increase in animals not receiving δ 9 -THC. δ 9 -THC resulted in a significant lowering of blood pressure in non-immobilized rats and blocked the appearance of hypertension in immobilized rats. These data support previous suggestions that THC compounds might be useful in an approach to the therapy of hypertension.
Psychopharmacology – Springer Journals
Published: Sep 1, 1973
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