Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Δ 9 -Tetrahydrocannabinol: A hypotensive effect in rats

Δ 9 -Tetrahydrocannabinol: A hypotensive effect in rats 213 28 28 3 3 R. B. Williams L. K. Y. Ng F. Lamprecht K. Roth I. J. Kopin Laboratory of Clinical Science and Laboratory of Clinical Psychobiology National Institute of Mental Health Bethesda Maryland Abstract The effects of δ 9 -tetrahydrocannabinol upon rat blood pressure were studied in control rats and in rats subjected to repeated immobilization stress over seven days. The immobilization stress was associated with a significant blood pressure increase in animals not receiving δ 9 -THC. δ 9 -THC resulted in a significant lowering of blood pressure in non-immobilized rats and blocked the appearance of hypertension in immobilized rats. These data support previous suggestions that THC compounds might be useful in an approach to the therapy of hypertension. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Psychopharmacology Springer Journals

Δ 9 -Tetrahydrocannabinol: A hypotensive effect in rats

Loading next page...
 
/lp/springer-journals/9-tetrahydrocannabinol-a-hypotensive-effect-in-rats-qthweIf1wT

References (11)

Publisher
Springer Journals
Copyright
Copyright © 1973 by Springer-Verlag
Subject
Biomedicine; Pharmacology/Toxicology; Psychiatry
ISSN
0033-3158
eISSN
1432-2072
DOI
10.1007/BF00429307
Publisher site
See Article on Publisher Site

Abstract

213 28 28 3 3 R. B. Williams L. K. Y. Ng F. Lamprecht K. Roth I. J. Kopin Laboratory of Clinical Science and Laboratory of Clinical Psychobiology National Institute of Mental Health Bethesda Maryland Abstract The effects of δ 9 -tetrahydrocannabinol upon rat blood pressure were studied in control rats and in rats subjected to repeated immobilization stress over seven days. The immobilization stress was associated with a significant blood pressure increase in animals not receiving δ 9 -THC. δ 9 -THC resulted in a significant lowering of blood pressure in non-immobilized rats and blocked the appearance of hypertension in immobilized rats. These data support previous suggestions that THC compounds might be useful in an approach to the therapy of hypertension.

Journal

PsychopharmacologySpringer Journals

Published: Sep 1, 1973

There are no references for this article.