Successful treatment of steroid-refractory systemic lupus erythematosus-associated protein-losing enteropathy using combination therapy with tacrolimus and steroid

H Li; X Zhang; J Chen

doi:10.1177/0961203311406766

$LUPsplupLupusLupus0961-20331477-0962SAGE PublicationsSage UK: London, England10.1177/096120331140676610.1177_0961203311406766Letters to the editorSuccessful treatment of steroid-refractory systemic lupus erythematosus-associated protein-losing enteropathy using combination therapy with tacrolimus and steroidLiHZhangXChenJKidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, P. R. ChinaJianghua Chen, Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, #79 Qingchun Road, Hangzhou, Zhejiang Province, P.R.China, 310003 Email: chenjianghua@zju.edu.cn10201120101109111116120111932011© The Author(s), 2011. Reprints and permissions: http://www.sagepub.co.uk/journalsPermissions.nav2011SAGE PublicationsSir,Protein-losing enteropathy (PLE) is an uncommon but very serious complication of systemic lupus erythematosus (SLE).1 Although most patients with SLE-associated PLE respond to corticosteroid treatment, a few cases are refractory to corticosteroids. In such cases, the addition of other immunosuppressive agents, such as cyclophosphamide and azathioprine, and even surgical resection of the involved intestinal section has been applied.2–4 However, the optimal therapy has not been established in cases that are refractory to corticosteroid treatment. Here we present a case of a woman patient with steroid-refractory SLE-associated PLE who was treated successfully with a combination therapy of tacrolimus and steroid.A 62-year-old Chinese woman was admitted to our department complaining of loose stools two or three times a day, and escalating swelling of face, feet, legs, and abdomen that had$

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Successful treatment of steroid-refractory systemic lupus erythematosus-associated protein-losing enteropathy using combination therapy with tacrolimus and steroid

Li, H; Zhang, X; Chen, J

Follow Lupus , Volume 20 (10) SAGE – Oct 1, 2011

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Successful treatment of steroid-refractory systemic lupus erythematosus-associated protein-losing enteropathy using combination therapy with tacrolimus and steroid

Li, H; Zhang, X; Chen, J

Follow Lupus , Volume 20 (10) SAGE – Oct 1, 2011

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