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Spironolactone (SPR), a mineralocorticoid receptor blocker, diminishes hyperglycemia-induced reduction in glucose - 6 - phosphate dehydrogenase (G6PD) activity, improving oxidative stress damage ...
and smoking cessation advice and ( 6 ) treatment of obesity. Defining and diagnosing diabetic kidney disease The terms diabetic nephropathy (DN) and diabetic kidney disease (DKD) are often used interchangeably ...
glucose -induced MCP-1 synthesis and NF-κB activation. Conclusions. These data suggest that pioglitazone not only improves insulin resistance, glycaemic control and lipid profile, but also ameliorates renal ...
of diabetes and progression to end-stage renal disease (ESRD). The ability of the antidiabetic drugs to delay nephropathy is as important as their capability to control glycaemia. While the lowering glucose ...
the potential effect that the mineralocoriticoid blockade may have on the improvement of renal function and structure when spironolactone is administrated immediately or even 6 h after an ischemic insult ...
CrossRef Search ADS PubMed 20 van den Meiracker AH, Baggen RG, Pauli S, et al. Spironolactone in type 2 diabetic nephropathy : effects on proteinuria, blood pressure and renal function, J Hypertens ...
reactivity by decreasing glucose - 6 - phosphate dehydrogenase activity . Nat Med 2007 ; 13 : 189 – 197 Google Scholar Crossref Search ADS PubMed 24 Barrera-Chimal J , Prince S , Fadel F et al. Sulfenic acid ...
Glucose Tolerance Outcomes Research (NAVIGATOR) trial.DIABETIC HEART DISEASELarge-scale clinical trials during the past 2 decades in particular have led to clinically significant improvements in survival ...
-tetrahydrobiopterin, as well as by activating protein phosphatase 2A.32 Leopold et al.33 showed that aldosterone decreased endothelial expression and activity of glucose - 6 - phosphate dehydrogenase (G6PD), which ...
A IMPROVES INSULIN SENSITIVITY AND OVERALL GLUCOSE TOLERANCE IN HCV-POSITIVE RENAL TRANSPLANT RECIPIENTS Ammon Handisurya Ammon Handisurya 1 Medical University of Vienna, Vienna, Austria Corinna Kerscher ...
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